2010 Fiscal Year Final Research Report
histological investigation of thermosensitivity in the laryngopharynx.
| Project/Area Number |
20592017
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Tottori University |
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Principal Investigator |
MIYAKE Naritomo Tottori University, 医学部・附属属病院, 医員 (60464278)
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| Co-Investigator(Kenkyū-buntansha) |
KAWAMOTO Katsuyuki 鳥取大学, 医学部, 助教 (50304217)
KITANO Hiroya 鳥取大学, 医学部, 教授 (20153108)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 温度受容 / 免疫染色 / VR1 / TRPM8 / TRPM5 |
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| Research Abstract |
It is not investigated in detail about thermosensitivity of laryngopharynx. We guess transiend receptor potential (TRP) family receptors have an intimate involvement in thermosensitivity of laryngopharynx. Most famous receptor is vanilloid receptor type 1(VR1) that is known as capsaicin receptor.
We use immunostaining method with VR1, PV5 and PM8 in dorsal root ganglion and trigeminal nerve of Rat. We found VR1 and TRPM positive neuron cell in dorsal root ganglion and trigeminal nerve.
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