2010 Fiscal Year Final Research Report
The effects of tissue perfusion for wound biofilm
| Project/Area Number |
20592096
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
ATSUSHI Takeda Tohoku University, 病院, 助教 (30333800)
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| Co-Investigator(Kenkyū-buntansha) |
MASAHIRO Tachi 東北大学, 大学院・医学系研究科, 教授 (50312004)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 創傷治癒 / 感染 / バイオフィルム / TNF-α |
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| Research Abstract |
Inoculation with Pseudomonas aeruginosa had accelerated re-epithelialization in rats wounds. Flow cytometry detected higher levels of TNF-a in the infiltrating neutrophils. Quorum sensing mutant induced delayed wound healing.
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