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2010 Fiscal Year Final Research Report

Pluripotency of somatic stem cells as new strategy for therapy of CNS regeneration.

Research Project

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Project/Area Number 20592109
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionSt.Marianna University School of Medicine

Principal Investigator

INOUE Hajime  St.Marianna University School of Medicine, 医学部, 准教授 (60193603)

Co-Investigator(Kenkyū-buntansha) TAKENAGA Mituko  聖マリアンナ医科大学, 医学(系)研究科(研究院), 准教授 (10236490)
TOMIOKA Miyuki  聖マリアンナ医科大学, 医学部, 研究技術員 (90398967)
Project Period (FY) 2008 – 2010
Keywords再生医学
Research Abstract

The hind limb paralysis with spinal cord injury improved significantly as compared to control group 1 to 6 week after human keratinocytes grafting. After scoring of bbb on motor function at 6week, the experimental rats, which were breed ad libitum, were observed for about 2 years. The keratinocytes grafted rats were shown the improvement of motor function and bladder and rectal disturbance symptom. From these results, to apply for clinical use, we prepare for the experiment of autologous keratinocytes grafted dog with a veterinarian.

  • Research Products

    (5 results)

All 2010 2009 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Book (1 results)

  • [Journal Article] 末梢組織細胞を用いた現実的再生医療とその治療戦略-幹細胞様細胞から多血小板血漿まで-2010

    • Author(s)
      井上肇、菅谷文人、千代倉友博、渡部雄一、相原正記、熊谷憲夫
    • Journal Title

      聖マリアンナ医科大学雑誌 38

      Pages: 第2・3

    • Peer Reviewed
  • [Journal Article] Re-epithelialization after laser therapy of a stenotic artificial tracheal graft.2008

    • Author(s)
      Tsukada H, Inoue H, Osada H
    • Journal Title

      Surgical Today 28

      Pages: 672-674

    • Peer Reviewed
  • [Presentation] 再生医療の実用化に向けた新規アプローチ-気管再生を中心に-2010

    • Author(s)
      井上肇
    • Organizer
      六医科大学合同新技術説明会
    • Place of Presentation
      東京
    • Year and Date
      2010-12-09
  • [Presentation] 各種材質による人工気管移植成績2009

    • Author(s)
      安藤幸二, 他
    • Organizer
      第26回日本呼吸器外科学会
    • Place of Presentation
      小倉
    • Year and Date
      2009-04-14
  • [Book] 培養表皮による創傷治療創傷外科に置ける新しいアプローチ(形成外科増刊号)2008

    • Author(s)
      熊谷憲夫、井上肇
    • Total Pages
      S255-S261
    • Publisher
      克誠堂出版(株)

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

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