2010 Fiscal Year Final Research Report
Protective effect of SOD on reactive oxygen species-induced salivary gland dysfunction.
| Project/Area Number |
20592161
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Morphological basic dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
YAMADA Hiroyuki Tsurumi University, 歯学部, 講師 (90267542)
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| Co-Investigator(Kenkyū-buntansha) |
SAITO Ichiro 鶴見大学, 歯学部, 教授 (60147634)
MISHIMA Kenji 鶴見大学, 歯学部, 准教授 (50275343)
INOUE Hiroko 鶴見大学, 歯学部, 講師 (50367306)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 活性酸素 / SOD |
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| Research Abstract |
Superoxide dismutase (SOD) is an antioxidant enzyme that eliminates one of reactive oxygen species (ROS) of superoxide. In this study, we examined the ability of SOD to restore ROS-induced salivary gland dysfunction. Our results suggested that SOD may protect against salivary gland dysfunction induced by ROS, presumably by rapidly converting superoxide to hydrogen peroxide.
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