2010 Fiscal Year Final Research Report

Development of the diagnostic treatment of a swallowing difficulty associated with dementia, using magnetoencephalography and diffusion MRI

Research Project

Project/Area Number	20592202
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Pathobiological dentistry/Dental radiology
Research Institution	Hiroshima University
Principal Investigator	NAGASAKI Toshikazu (山田信一) Hiroshima University, 医歯薬学総合研究科, 助教 (10263724)
Co-Investigator(Kenkyū-buntansha)	YOSHIKAWA Mineka 広島大学, 医歯薬学総合研究科, 助教 (00444688) TANIMOTO Keiji 広島大学, 医歯薬学総合研究科, 教授 (10116626)
Project Period (FY)	2008 – 2010
Keywords	脳磁図 / 食物認知
Research Abstract	We studied cortical activity of food cognition using magnetoencephalography and tractgraphy. Neuromagnetic activities in 14 healthy female volunteers (24-35 years old, all right-handed) were recorded while fasting. Four types of visual stimuli-food picture, non-food picture, food name, and non-food name--were presented in random order. Subjects were instructed to judge whether items were food or non-food immediately after presentation and think nothing after judgment. Cerebral activities were evaluated by visual inspection of the topographies. Food items resulted in higher activity of beta band in the left around posterior parts of superior temporal gyrus, than did non-food items. Visual stimulation with food judge is possibility to relate Wernicke area.