2010 Fiscal Year Final Research Report
Basic Study of Direct Pulp Capping Materials
| Project/Area Number |
20592241
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Nihon University |
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Principal Investigator |
HAYASHI Makoto Nihon University, 歯学部, 准教授 (00301557)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 直接覆髄剤 / 歯髄細胞 / 硬組織形成 / 細胞増殖 / アルカリフォスファターゼ |
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| Research Abstract |
Dental pulp has many important roles, and the most severe problem of removing it would be tooth fracture. Therefore, dental treatment to preserve dental pulp is very important for dentists. The aim of this study is to develop new materials for direct pulp capping (i.e., treatment for protection of dental pulp). Five-aminoimidazole-4- carboxamide-1-β-4-ribofuranoside (AICAR), Titanium Medical Apatite (TMA), Calcium Phosphate Cement (CPC) were used to evaluate the possibility of being direct pulp capping materials in this study. Results indicated high biocompatibility and promotion of differentiation in some experimental conditions.
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