2010 Fiscal Year Final Research Report
Expression of MMPs and TIMPS in development of rat periradicular lesion
| Project/Area Number |
20592243
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
IMAIZUMI Ichiro Aichi Gakuin University, 歯学部, 講師 (20308779)
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| Co-Investigator(Kenkyū-buntansha) |
NAKAMURA Hiroshi 愛知学院大学, 歯学部, 教授 (40064878)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 根尖病変 / MMP-8 / MMP-13 / TIMP1 / TIMP2 |
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| Research Abstract |
To elucidate the expressions of MMP-8, MMP-13,TIMP1 and TIMP2 in experimentally induced rat periradicular lesions by means of the reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemical staining.
These findings indicate that MMP-8, MMP-13,TIMP1 and TIMP2 were related to the development of periradicular lesions.
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