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2010 Fiscal Year Final Research Report

Using alveolar bone tissue to diagnose early-stage osteoporosis : The establishment of a dentistry-based technique-

Research Project

  • PDF
Project/Area Number 20592259
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Prosthetic dentistry
Research InstitutionNiigata University

Principal Investigator

TANAKA Mikako  Niigata University, 医歯学総合病院, 講師 (20361909)

Co-Investigator(Kenkyū-buntansha) SADAKAZU Ejiri  朝日大学, 歯学部, 教授 (40160361)
KAZUHO Yamada  新潟大学, 医歯学総合病院, 医員 (20397152)
AKIRA Matsuo  東京医科大学, 医学部, 准教授 (70229417)
NORIAKI Yamamoto  新潟医療福祉大学, 骨の科学研究所, 転倒予防センター所長 (30445902)
NAOKI Sakurai  新潟大学, 医歯学系, 助教 (50251830)
Project Period (FY) 2008 – 2010
Keywords歯科補綴学一般 / 骨粗鬆症
Research Abstract

The present study used bone biopsy samples extracted during dental implant preparation, for investigating microstructural changes in alveolar cancellous bone due to menopause, and elucidating relationships between these changes and bone turnover markers.
In the alveolar cancellous bone, bone volume was found to be significantly less in late postmenopausal group than in premenopausal group. In early postmenopausal group, trabecular separation and structure model index (SMI) were significantly higher than in premenopausal group. Each alveolar bone parameter was significantly related to at least one bone turnover marker. The present study therefore revealed changes in alveolar cancellous bone structure even in early postmenopausal women, and also that this structure varies in close relationship to bone turnover markers.

  • Research Products

    (10 results)

All 2011 2010 2009 2008 Other

All Journal Article (2 results) Presentation (7 results) Remarks (1 results)

  • [Journal Article] Radiological and histologic studies of the mandibular cortex of ovariectomized monkeys2011

    • Author(s)
      Tanaka M, Yamashita E, Anwar B.R, Yamada K, Ohshima H, Nomura S, Ejiri S
    • Journal Title

      Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111(3)

      Pages: 372-380

  • [Journal Article] Estrogen deficiency and its effect on the jaw bones.2008

    • Author(s)
      Ejiri S, Tanaka M, Watanabe N, Anwar B.R, Yamashita E, Yamada K, Ikegame M
    • Journal Title

      J Bone Miner Metab 26(5)

      Pages: 409-415

  • [Presentation] 歯槽骨を用いた骨粗鬆症診断の可能性を探る-歯槽骨骨構造と骨代謝マーカーとの関連性-.2010

    • Author(s)
      山下絵美, 田中みか子, 野村修一, 江尻貞一
    • Organizer
      第21回日本老年歯科医学会総会・学術大会,老年歯学
    • Place of Presentation
      新潟
    • Year and Date
      20100625-20100626
  • [Presentation] ヒト歯槽骨の骨構造と全身の骨代謝マーカーとの関係.2010

    • Author(s)
      山下絵美, 田中みか子, 櫻井直樹, 山田一穂, 荒井良明, 魚島勝美, 野村修一, 江尻貞一
    • Organizer
      日本補綴歯科学会第119回学術大会,日補綴会誌,2(第119回特別号): 94.
    • Place of Presentation
      東京
    • Year and Date
      20100611-20100613
  • [Presentation] 第30回日本骨形態計測学会,学術奨励賞.ヒト歯槽骨生検試料の骨構造および骨塩量と全身の骨代謝マーカーとの関係.2010

    • Author(s)
      山下絵美, 田中みか子, 松尾朗, 野村修一, 江尻貞一
    • Organizer
      第30回日本骨形態計測学会,日骨形態誌
    • Place of Presentation
      米子
    • Year and Date
      20100000
  • [Presentation] 歯槽骨生検試料を用いた全身骨動態スクリーニングの試み.2009

    • Author(s)
      山下絵美, 田中みか子, 松尾 朗, 野村修一, 江尻貞一
    • Organizer
      第29回日本骨形態計測学会,骨形態誌
    • Place of Presentation
      大阪
    • Year and Date
      20090000
  • [Presentation] Microstructural and histological studies of the mandibular cortex of ovariectomized monkeys.2008

    • Author(s)
      Tanaka M, Yamashita E, Anwar RB, Ohshima H, Nomura S, Ejiri S
    • Organizer
      The 38th international Sun Valley workshop on skeletal tissue biology, Sun Valley, Idaho
    • Place of Presentation
      USA
    • Year and Date
      20080000
  • [Presentation] Relationship between estrogen deficiency-induced oral bone loss and systemic osteoporosis.2008

    • Author(s)
      Anwar RB, Tanaka M, Yamashita E, Watanabe N, Ali MN, Ohshima H, Ejiri S
    • Organizer
      The 38th international Sun Valley workshop on skeletal tissue biology, Sun Valley, Idaho
    • Place of Presentation
      USA
    • Year and Date
      20080000
  • [Presentation] Micro-structural observation and histological analysis of human alveolar bone biopsy from an implant recipient site.2008

    • Author(s)
      Yamashita E, Tanaka M, Sakurai N, Anwar RB, Nomura S, Ohshima H, Ejiri S
    • Organizer
      The 38th international Sun Valley workshop on skeletal tissue biology, Sun Valley, Idaho
    • Place of Presentation
      USA
    • Year and Date
      20080000
  • [Remarks] ホームページ等

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Published: 2012-01-26   Modified: 2016-04-21  

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