2010 Fiscal Year Final Research Report
Management of dry mouth ; Influence of mucin on oral dryness
| Project/Area Number |
20592348
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
NAKAGAWA Yoichi Tsurumi University, 歯学部, 講師 (90148057)
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| Project Period (FY) |
2008 – 2010
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| Keywords | ドライマウス / ムチン / カンジダ |
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| Research Abstract |
Mucin is a glycoprotein found in saliva, which have multiple activities in maintaining the health of the oral mucosa. The purpose of the study was to investigate the salivary mucin level in the dry mouth patients, and to investigate the relationship between the mucin level and Candida colonization on the oral mucosa. The results demonstrated that the salivary mucin was low in the dry mouth patients, and inverse relationship between mucin and Candida was recognized, suggesting that salivary mucin inhibit the Candida colonization.
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