2010 Fiscal Year Final Research Report

Management of dry mouth ; Influence of mucin on oral dryness

Research Project

Project/Area Number	20592348
Research Category	Grant-in-Aid for Scientific Research (C)
Allocation Type	Single-year Grants
Section	一般
Research Field	Surgical dentistry
Research Institution	Tsurumi University
Principal Investigator	NAKAGAWA Yoichi Tsurumi University, 歯学部, 講師 (90148057)
Project Period (FY)	2008 – 2010
Keywords	ドライマウス / ムチン / カンジダ
Research Abstract	Mucin is a glycoprotein found in saliva, which have multiple activities in maintaining the health of the oral mucosa. The purpose of the study was to investigate the salivary mucin level in the dry mouth patients, and to investigate the relationship between the mucin level and Candida colonization on the oral mucosa. The results demonstrated that the salivary mucin was low in the dry mouth patients, and inverse relationship between mucin and Candida was recognized, suggesting that salivary mucin inhibit the Candida colonization.

(4 results)