2010 Fiscal Year Final Research Report
The elucidation of Bone Remodeling Change of EPH/ephrin signal with the Aging
| Project/Area Number |
20592389
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KOIKE Mariko Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 (50376779)
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| Co-Investigator(Kenkyū-buntansha) |
MATSUMOTO Yoshiro 東京医科歯科大学, 医歯学総合研究科, 講師 (20292980)
KANEKO Sawa 東京医科歯科大学, 医歯学総合研究科, 助教 (80372449)
HOSOMICHI Jyun 東京医科歯科大学, 医歯学総合研究科, 助教 (00420258)
WATARI Ippei 東京医科歯科大学, 医歯学総合研究科, 助教 (10431941)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 老化 / 骨リモデリング / 歯周組織 |
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| Research Abstract |
The changes in periodontal tissue with growth and aging were analyzed. The expression of CGRP-ir nerve fibers in the PDL is most active in the growth period and decreases gradually with aging. Moreover, age-related decreases in the expression of bFGF may delay the regeneration of the periodontal ligament. Such an effect may act unfavorably in the case of tooth movement.
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Research Products
(11 results)
