2010 Fiscal Year Final Research Report
Biologic pathways for the relationship between periodontitis and cardiovascular disease
Project/Area Number |
20592426
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Periodontal dentistry
|
Research Institution | Niigata University |
Principal Investigator |
TABETA Koichi Niigata University, 超域研究機構, 准教授 (20401763)
|
Co-Investigator(Kenkyū-buntansha) |
山崎 和久 新潟大学, 医歯学系, 教授 (00182478)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 歯周炎 / Porphyromonas gingivalis / エイジング / 動脈硬化症 / マウスモデル |
Research Abstract |
Periodontal infection itself does not cause atherosclerosis, but it accelerates it by inducing systemic inflammation and deteriorating lipid metabolism, particularly when underlying hyperlipidemia or susceptibility to hyperlipidemia exists, and it may contribute to the development of coronary heart disease. Further study is undertaken related to aging.
|