2010 Fiscal Year Final Research Report
Effects of Smoking and Passive Smoking in Oral Host Defense Functions.
| Project/Area Number |
20592437
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | The Nippon Dental University |
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Principal Investigator |
NUMABE Yukihiro The Nippon Dental University, 生命歯学部, 教授 (90198557)
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| Co-Investigator(Kenkyū-buntansha) |
ITO Hiroshi 日本歯科大学, 生命歯学部, 准教授 (30184683)
SUZUKI Asami 日本歯科大学, 生命歯学部, 助教 (60318540)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 唾液 / 能動喫煙 / 受動喫煙 / 好中球 |
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| Research Abstract |
The present study focused on the relationship between cigarette smoking (first and second hand smoking) and changes of various oral host defense functions in healthy or periodontitis patients. These findings suggest that the effect of smoking was enhanced in periodontitis patients and substances in cigarette smoke could impaired immunological functions (decreasing PMN functions and increasing enzyme activities which associated with tissue destruction) in the oral cavity in smokers or passive smokers.
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