2010 Fiscal Year Final Research Report
Periodontal tissue regeneration by a novel bone-forming peptide
| Project/Area Number |
20592442
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Periodontal dentistry
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| Research Institution | Osaka Dental University |
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Principal Investigator |
TANAKA AKIO Osaka Dental University, 歯学部, 教授 (10121823)
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| Co-Investigator(Kenkyū-buntansha) |
TOMINAGA Kazuya 大阪歯科大学, 歯学部, 講師 (80278572)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 歯学 / 再生医学 / 病理学 / 細胞・組織 / 生体分子 |
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| Research Abstract |
We investigated whether synthesized oligopeptide is useful or not for periodontal tissue regeneration. Cementum-like tissues were observed in the removed surface of dentin in the tissue defect area. Moreover, formation of dentin-like or cementum-like hard tissues was observed in the dentin surface in the defect area toward the surface epithelium. Based on these results, it is suggested that oligopeptide has a potential to induce hard tissue formation in defects of the periodontal tissue.
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