2010 Fiscal Year Final Research Report
Research into amino acid racemization rates in hard tissues.
| Project/Area Number |
20592474
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Social dentistry
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| Research Institution | Kanagawa Dental College |
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Principal Investigator |
OHTANI Susumu Kanagawa Dental College, 高次口腔科学研究所, 教授 (60104478)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 法医学 / 年齢推定 / 硬組織 / D-アスパラギン酸 / ラセミ化率 |
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| Research Abstract |
Few reports in the literature have investigated amino acid racemization. Aspartic acid (Asp) is rapidly converted from L-Asp to D-Asp, and the racemization rate increases constantly with aging. Racemization rates can be used in the field of age estimation, one of the most important aspects of forensic medicine. We are one of the world leaders in the application of racemization rates to age estimation using teeth (dentin), and our studies have yielded satisfactory results (r=0.99). To further advance our research, we studied the use of heated teeth and non-Japanese teeth, and investigated the relationship between DNA analysis and racemization rates.
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