The relationship between calcification nano particle and dentalcariculus

2010 Fiscal Year Final Research Report

• Project/Area Number: 20592475
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Social dentistry
• Research Institution: National Institute of Public Health
• Principal Investigator: TAMAKI Yoh National Institute of Public Health, 政策科学部, 主任研究官 (50386827)
• Co-Investigator(Kenkyū-buntansha): NOMURA Yoshiaki 鶴見大学, 歯学部・探索歯学講座, 准教授 (90350587)
• Project Period (FY): 2008 – 2010
• Keywords: 歯周病 / 歯石 / 異所性石灰化 / 石灰化ナノ粒子

Research Abstract

We find out that the Calcificaton Nano Particle(CNPs) is existed both in human serum and saliva. The bovine serum protein separated by the high performance liquid chromatography were reacted to the monoclonal antibody for the CNPs. And these proteins were strongly attached to the hydroxyapatite. These results suggested that the CNPs may contribute to the dental calculus formation.

Research Products

• [Journal Article] Effects of Coenzyme Q10 on Salivary Secretion. (2011)
  • Author(s): Ryo K, Ito A, Takatori R, Tai Y, Arikawa K, Seido T, Yamada T, Shinpo K, Tamaki Y, Fujii K, Yamamoto Y, Saito I
  • Journal Title: Clinical Biochemistry. Clinical Biochemistry 44 Pages: 669-674
• [Journal Article] 地域住民を対象とした歯間ブラシの使用に重点をおいた歯周病予防のための健康教育プログラムの効果 (2011)
  • Author(s): 山崎洋治,湯之上志保,山口敏子,細久保和美,武儀山,武井,高田康二,中安美枝子,石川昭,中村宗達,玉置洋,野村義明,花田信弘
  • Journal Title: 口腔衛生学会誌 61(1) Pages: 13-21
• [Journal Article] Evaluation of Therapeutic of Astaxanthin on Impairments in Salivary Secretion. (2010)
  • Author(s): Yamada T, Ryo K, Tai Y, Tamaki Y, Inoue H, Mishima K, Tsubota K, Saito I
  • Journal Title: J.Clin.Biochem. 47 Pages: 130-137
• [Journal Article] HSPA1A is upregulated in periodontal ligament at early stage of tooth movement in rats. (2010)
  • Author(s): Arai C, Nomura Y, Ishikawa M, Noda K, Choi JW, Yashiro Y, Hanada N, Nakamura Y
  • Journal Title: Histochem Cell Biol.(Epub 2010 Sep 1) 134(4) Pages: 337-43
• [Journal Article] Construction of a dental caries prediction model by data mining. (2009)
  • Author(s): Tamaki Y, Nomura Y, Katsumura S, Okada A, Yamada H, Tsuge S, Kadoma Y, Hanada N
  • Journal Title: J Oral Sci. 51(1) Pages: 61-8
• [Journal Article] Bonding durability against water of a fluorine-containing resin for precious metal alloys. (2009)
  • Author(s): Kadoma Y, Tamaki Y
  • Journal Title: Dent Mater J. 28(5) Pages: 642-648
• [Journal Article] Fluoride Intake from Tea in Japanese Infants. (2009)
  • Author(s): Kubota K, Kuroha K, Kawata K, Komiyama E, Tamaki Y, Uematsu M, Arakawa H
  • Journal Title: Int J Oral Health. 5 Pages: 7-15
• [Journal Article] 中学生と高校生における歯の摩損に関する研究 (2009)
  • Author(s): 黒羽加寿美,久保田友嘉,荒川勇喜,川田和重,宋文群,戸田真司,川村和章,木本一成,玉置洋,荒川浩久
  • Journal Title: 口腔衛生学会雑誌 59(5) Pages: 577-585
• [Journal Article] Asymmetry of the lips of orthognathic surgery patients. (2009)
  • Author(s): Yamashita Y, Nakamura Y, Shimada T, Nomura Y, Hirashita A
  • Journal Title: Am J Orthod Dentofacial Orthop. 136(4) Pages: 559-63
• [Journal Article] Morphological changes in the rat periodontal ligament and its vascularity after experimental tooth movement using superelastic forces. (2009)
  • Author(s): Noda K, Nakamura Y, Kogure K, Nomura Y
  • Journal Title: Eur J Orthod.(Epub 2008 Dec 10) 31(1) Pages: 37-45
• [Journal Article] Community based screening for periodontitis using salivary test : Bulletein of Kanagawa Dental College (2008)
  • Author(s): Furuya M, Nomura Y, Tamaki Y, Sato T, Hanada N, Kamoi K, Arakawa H
  • Journal Title: 36(1) Pages: 3-9
• [Journal Article] Factors affecting the oral condition of patients with severe motor and intellectual disabilities. (2008)
  • Author(s): IdairaY, Nomura Y, Tamaki Y, Katsumura S, Kodama S, Kurata K, AsadaY
  • Journal Title: Oral Diseases. 14 Pages: 435-9
• [Presentation] 横須賀地区海上自衛隊員の喫煙状況と歯周疾患の関連性 (2011)
  • Author(s): 海老沢政人、玉置洋、有井丈朗、清水彰一郎
  • Organizer: 第56回防衛衛生学会(防衛衛生、第58巻別冊Vol.58.2011.P106)
  • Place of Presentation: 東京
  • Year and Date: 2011-02-03
• [Presentation] 喫煙状況による歯周疾患リスクの解析 (2010)
  • Author(s): 海老沢政人、玉置洋、有井丈朗、大小田学、五味一博、新井高
  • Organizer: 第53回日本歯周病学会秋期学術大会(日本歯周病学会会誌52秋期特別号p99)
  • Place of Presentation: 高松
  • Year and Date: 2010-09-19
• [Presentation] ベイジアンネットワークを用いた齲蝕リスク評価の試み (2009)
  • Author(s): 玉置洋、勝村聖子、柘植紳平、野村義明、花田信弘
  • Organizer: 第58回日本口腔衛生学会(口腔衛生学会雑誌59(4)p513)
  • Place of Presentation: 岐阜
  • Year and Date: 2009-10-11
• [Presentation] Improved screening for periodontal diseases using salivary biochemical markers and statistical modering. (2009)
  • Author(s): Nomura Y, Tamaki Y, A Eto, Ogino D, Nakamura Y, N Takahashi, F Hino, Koresawa K, Hanada N, Shimizu K
  • Organizer: IADR PAPF/APR/JADR
  • Place of Presentation: Wuhan China
  • Year and Date: 2009-10-03
• [Presentation] 防衛省海上自衛隊における艦艇勤務者と陸上勤務者のう蝕罹患状況の比較 (2008)
  • Author(s): 田島聖士,海老沢政人,玉置洋,野村義明,花田信弘
  • Organizer: 第57回日本口腔衛生学会・総会(口腔衛生学会雑誌58(4)p350)
  • Place of Presentation: 埼玉
  • Year and Date: 20081002-20081004
• [Presentation] 学童期追跡調査における齲蝕リスクファクターの評価 (2008)
  • Author(s): 勝村聖子,玉置洋,野村義明,柘植紳平,花田信弘
  • Organizer: 第57回日本口腔衛生学会・総会(口腔衛生学会雑誌58(4)p445)
  • Place of Presentation: 埼玉
  • Year and Date: 20081002-20081004
• [Presentation] 唾液中のクロモグラニンAを指標としたストレス反応のパターン化 (2008)
  • Author(s): 篠原佐知緒、玉置洋、伊平弥生、栗山千裕、朝田芳信
  • Organizer: 第46回日本小児歯科学会大会(抄録集小児歯科学雑誌、46(2)p214)
  • Place of Presentation: 埼玉
  • Year and Date: 20080612-20080613
• [Remarks] ホームページ等