2011 Fiscal Year Final Research Report
Research for exploring of novel target enzymes of organophosphorous compounds
| Project/Area Number |
20599022
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental pharmacy
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| Research Institution | National Research Institute of Police Science |
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Principal Investigator |
TSUGE Kouichiro 科学警察研究所, 法科学第三部, 主任研究官 (90356204)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 神経ガス / サリン / メタミドホス / 質量分析法 / プロテオーム / 中毒 |
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| Research Abstract |
To explore the novel target enzymes for organophosphorous compound, we established the analytical method for specific detection of OP-combined peptide, using the shotgun proteomics procedure. To apply this method for the complicated sample such as serum, we adopted the purification procedure using TiO2, ZrO2 pre treatment column.
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