2010 Fiscal Year Final Research Report
In vivo patch-clamp analysis of plastic changes in descending inhibitory system
| Project/Area Number |
20602003
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
疼痛学
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| Research Institution | Kyushu University |
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Principal Investigator |
FURUE Hidemasa Kyushu University, 生体情報研究系, 准教授 (20304884)
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| Co-Investigator(Kenkyū-buntansha) |
YOSHIMURA Megumu 九州大学, 医学研究院, 教授 (10140641)
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIMURA Megumu 熊本保健科学大学, 保健科学部, 教授 (10140641)
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| Project Period (FY) |
2008 – 2010
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| Keywords | シナプス / 感覚 / ノルアドレナリン / 鎮痛 / 青斑核 |
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| Research Abstract |
Descending noxious inhibitory system was studied by using in vivo patch-clamp recording technique. The present main finding is that stimulating the locus coeruleus enhances spinal inhibitory synaptic transmission.
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