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2010 Fiscal Year Final Research Report

Effects of exercise on immobilization-induced pain and its prevention

Research Project

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Project/Area Number 20602008
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 疼痛学
Research InstitutionNagoya Gakuin University

Principal Investigator

KOEDA TOMOKO  Nagoya Gakuin University, リハビリテーション学部, 准教授 (20223050)

Co-Investigator(Kenkyū-buntansha) NISHIGAMI Tomohiko  甲南女子大学, 看護リハビリテーション学部, 准教授 (60515691)
Co-Investigator(Renkei-kenkyūsha) MIZUMURA Kazue  名古屋大学, 環境医学研究所, 教授 (00109349)
Research Collaborator OKUMURA Syoji  名古屋学院大学
NISHII Chihiro  東名ブレース株式会社
Project Period (FY) 2008 – 2010
Keywords不動化ラット / 疼痛閾値 / ストレッチング / トレッドミル走 / 運動習慣
Research Abstract

The purpose of this study was to examine whether the immobilization-induced pain was influenced by some therapeutic exercises. Cast was placed at the ankle in full plantar flexed position for 4 weeks. Rats exercised by treadmill running for 15 min/day, free moving for 15 min/day or stretching for 30 min/day, 5-6 days/week during immobilization period. The nociception behaviors in free moving and stretching group were decreased compared with rats received immobilization only. Moreover, it was clarified that the pain was reduced by treadmill running before immobilization.

  • Research Products

    (24 results)

All 2011 2010 2009 2008

All Journal Article (19 results) (of which Peer Reviewed: 13 results) Presentation (3 results) Book (2 results)

  • [Journal Article] 関連痛部位に対する圧刺激は関連痛を軽減させる2011

    • Author(s)
      肥田朋子、柴田莉紗、他
    • Journal Title

      Pain Rehabil 1

      Pages: 7-11

    • Peer Reviewed
  • [Journal Article] Muscle Meterによる筋の硬さ測定-他の筋硬度計との有用性の比較-2010

    • Author(s)
      天野幸代、肥田朋子
    • Journal Title

      名古屋学院大学論集 47(2)

      Pages: 83-9

  • [Journal Article] 痛み刺激による前頭前野の即時的な脳血流量変化2010

    • Author(s)
      西上智彦、池本竜則、他
    • Journal Title

      Pain Res 25(3)

      Pages: 127-134

  • [Journal Article] 痛みに対するリハビリテーション-脳科学・痛み学の視点からのアプローチ-2010

    • Author(s)
      西上智彦, 渡邉晃久
    • Journal Title

      認知運動療法研究 9

      Pages: 83-107

    • Peer Reviewed
  • [Journal Article] Bradykinin and nerve growth factor play pivotal roles in muscular mechanical hyperalgesia after exercise (delayed-onset muscle soreness).2010

    • Author(s)
      Murase S, Mizumura K, et al.
    • Journal Title

      J Neurosci 30(10)

      Pages: 3752-3761

    • Peer Reviewed
  • [Journal Article] Persistent deep mechanical hyperalgesia induced by repeated cold stress in rats.2010

    • Author(s)
      Nasu T, Taguchi T, Mizumura K
    • Journal Title

      Eur J Pain 14(3)

      Pages: 236-244

    • Peer Reviewed
  • [Journal Article] Augmented mechanical response of muscular thin-fiber receptors in aged rats recorded in vitro.2010

    • Author(s)
      Taguchi T, Mizumura K
    • Journal Title

      Eur J Pain. (In press)

    • Peer Reviewed
  • [Journal Article] ラット足関節不動化による活動制限は痛みを促進する2009

    • Author(s)
      山本綾、肥田朋子、他
    • Journal Title

      理学療法学 36(6)

      Pages: 305-311

  • [Journal Article] 筋硬度計による生体の硬さ測定-再現性と妥当性と有用性-2009

    • Author(s)
      肥田朋子、天野幸代
    • Journal Title

      名古屋学院大学論集 46(2)

      Pages: 55-61

  • [Journal Article] Increased pain from muscle fascia following eccentric exercise : animal and human findings.2009

    • Author(s)
      Gibson W, Arent-Nielsen L, Taguchi T, Mizumura K, Graven-Nielsen T
    • Journal Title

      Exp Brain Res 194(2)

      Pages: 299-308

    • Peer Reviewed
  • [Journal Article] Excitatory actions of mushroom poison (acromelic acid) on unmyelinated muscular afferents in the rat.2009

    • Author(s)
      Taguchi T, Tomotoshi K, Mizumura K
    • Journal Title

      Neurosci Lett 456(2)

      Pages: 69-73

    • Peer Reviewed
  • [Journal Article] Peripheral mechanism of muscle pain : An update.2009

    • Author(s)
      Mizumura K
    • Journal Title

      Current Anaesthesia & Critical Care 20

      Pages: 183-7

  • [Journal Article] Changes in calcitonin gene-related peptide expression following joint immobilization in rats2009

    • Author(s)
      Nishigami T, 他
    • Journal Title

      Neurosci Lett 454(1)

      Pages: 97-100

    • Peer Reviewed
  • [Journal Article] 運動器の不動化に伴う神経系の変化2009

    • Author(s)
      大迫洋治, 西上智彦, 他
    • Journal Title

      ペインクリニック 30(9)

      Pages: 1239-1248

  • [Journal Article] 両側変形性股関節症に対して片側人工股関節置換術を施行した症例の非術側に股関節牽引療法を行った効果について2009

    • Author(s)
      西上智彦, 若松志帆, 他
    • Journal Title

      理学療法科学 24(4)

      Pages: 613-615

    • Peer Reviewed
  • [Journal Article] Changes in calcitonin gene-related peptide expression following joint immobilization in rats2009

    • Author(s)
      Nishigami T, Osako Y, 他
    • Journal Title

      Neuroscience Letters. Vol.454 No.1

      Pages: 97-100

    • Peer Reviewed
  • [Journal Article] Compression-induced ATP release from rat skeletal muscle with and without lengthening contraction.2008

    • Author(s)
      Taguchi T, Kozaki Y, Katanosaka K, Mizumura K
    • Journal Title

      Neurosci Lett 434(3)

      Pages: 277-281

    • Peer Reviewed
  • [Journal Article] TRP channels and ASICs mediate mechanical hyperalgesia in models of inflammatory muscle pain and delayed onset muscle soreness.2008

    • Author(s)
      Fujii Y, Mizumura K, 他
    • Journal Title

      Pain 140(2)

      Pages: 292-304

    • Peer Reviewed
  • [Journal Article] 変形性膝関節症に対する理学療法とバイオメカニクス2008

    • Author(s)
      西上智彦, 奥埜博之, 中尾聡志, 芥川知彰, 榎勇人
    • Journal Title

      理学療法ジャーナル 42(10)

      Pages: 837-846

    • Peer Reviewed
  • [Presentation] Casting of ankle joint induces nociception in rats.2010

    • Author(s)
      Koeda T, Mizumura K, et al.
    • Organizer
      13th World Congress on Pain
    • Place of Presentation
      Palais de congres de Montreal (Montreal, Canada)
    • Year and Date
      2010-09-01
  • [Presentation] COX-2-GDNF pathway to delayed onset muscle soreness in rats.2010

    • Author(s)
      Murase S, Queme F, Taguchi T, Mizumura K
    • Organizer
      13th World Congress on Pain
    • Place of Presentation
      Palais de congres de Montreal (Montreal, Canada)
    • Year and Date
      2010-08-31
  • [Presentation] 不動化に伴う疼痛発生に対する運動の影響~不動化モデルラットを用いて~2010

    • Author(s)
      肥田朋子, 他
    • Organizer
      第15回理学療法の医学的基礎研究会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-05-26
  • [Book] 急性痛(沖田実他編)(機能障害科学入門)2010

    • Author(s)
      肥田朋子
    • Total Pages
      21-41
    • Publisher
      神陵文庫(福岡)
  • [Book] Facilitated response of muscle receptors after eccentric contraction.(Arandt-Nielsen L, Graven-Nielsen T, Mense S, eds.)(Fundamentals of Musculoskeletal Pain.)2008

    • Author(s)
      Mizumura K, Taguchi T.
    • Total Pages
      47-59
    • Publisher
      IASP Press(Seattle)

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Published: 2012-01-26   Modified: 2014-07-08  

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