2011 Fiscal Year Final Research Report
Chemical-biological Study on the Bioactive Compounds from Marine Algae
| Project/Area Number |
20611012
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Chemical biology
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| Research Institution | Hiroshima University |
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Principal Investigator |
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| Project Period (FY) |
2008 – 2011
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| Keywords | 赤潮プランクトン / 渦鞭毛藻 / ヘテロカプサ・サーキュラリスカーマ / 構造決定トレーサー分子 / 有機触媒 / 二枚貝致死活性物質 / 構造活性相関 |
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| Research Abstract |
In order to elucidate the chemical structures of the toxic substances and the biological activities of the harmful phytoplankton, Heterocapsa circularisquama caused mass mortalities of bivalves, e. g. oyster, the spectroscopic analyses of toxic compounds and the chemical degradation reactions were carried out. Also, in order to construct the the partial structure of the toxic compounds, the novel organocatalyst which catalyzed for the enantioselective aldol and Michael reactions and the desymmetrization of symmetric alcohols were developed.
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