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2010 Fiscal Year Final Research Report

Selective Removal of Cholesteryl Ester by Mid-infrared Tunable Nanosecond Pulsed Laser

Research Project

  • PDF
Project/Area Number 20612006
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Quantum beam science
Research InstitutionOsaka University

Principal Investigator

AWAZU Kunio  Osaka University, 工学研究科, 教授 (30324817)

Co-Investigator(Kenkyū-buntansha) ISHII Katsunori  大阪大学, 工学研究科, 助教 (20512073)
Project Period (FY) 2008 – 2010
Keywordsレーザー治療 / 粥状動脈硬化症 / レーザー血管形成術 / 中赤外レーザー / 差周波発生
Research Abstract

The purpose of this study is to develop a novel less-invasive laser angioplasty. In this study, we examined the removal of atherosclerotic tissue by using the mid-infrared tunable nanosecond pulsed laser with a wavelength at 5.75μm. Selective removal of atherosclerotic tissue without a side effect to normal was observed. This technique does not perforate a vessel wall compared with a conventional excimer laser angioplasty and realize a safe treatment of atherosclerosis.

  • Research Products

    (11 results)

All 2010 2009 2008

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (5 results) Book (1 results)

  • [Journal Article] Less-invasive Laser Therapy and Diagnosis using a Tabletop Mid-infrared Tunable laser2010

    • Author(s)
      間久直, 石井克典, 粟津邦男
    • Journal Title

      Journal of Innovative Optical Health Sciences 3(4)

      Pages: 285-292

    • Peer Reviewed
  • [Journal Article] Selective Treatment of Atherosclerotic Plaques using Nanosecond Pulsed Laser with a Wavelength of 5.75 μm for Less-invasive Laser Angioplasty2009

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Journal Title

      Proceedings of SPIE 7373

      Pages: 73731E

    • Peer Reviewed
  • [Journal Article] 波長5.75μmのナノ秒パルスレーザーによる低侵襲なレーザー血管形成術の開発2009

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Journal Title

      日本レーザー医学会誌 30(2)

      Pages: 126-134

    • Peer Reviewed
  • [Journal Article] Selective Removal of Cholesteryl Ester in Atherosclerotic Plaque by Nanosecond Pulsed Laser at 5.75 μm for Less-invasive Laser Angioplasty2009

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Journal Title

      Proceedings of SPIE 7161

      Pages: 71612T

    • Peer Reviewed
  • [Journal Article] 波長5.75μmのナノ秒パルスレーザーによる粥状動脈硬化症の低侵襲血管形成術の開発2008

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Journal Title

      生体医工学 46(5)

      Pages: 529-535

    • Peer Reviewed
  • [Presentation] Development of Selective Laser Treatment Techniques using Mid-infrared Tunable Nanosecond Pulsed Laser2010

    • Author(s)
      K.Ishii, M.Saiki, H.Hazama, K.Awazu
    • Organizer
      32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE EMBC 2010)
    • Place of Presentation
      Sheraton Buenos Aires Hotel & Convention Center, Buenos Aires, Argentina.
    • Year and Date
      20100831-20100904
  • [Presentation] 波長5.75μmのレーザー血管形成術の開発-アブレーション飛散物及び血管内治療カテーテルの検討-2010

    • Author(s)
      月元秀樹, 石井克典, 間久直, 粟津邦男
    • Organizer
      レーザー学会学術講演会第30回年次大会
    • Place of Presentation
      千里ライフサイエンスセンター,大阪府豊中市
    • Year and Date
      20100202-20100204
  • [Presentation] In-vitro Study of Novel Less-invasive Laser Angioplasty using the Pulsed Laser with a Wavelength of 5.75 μm2009

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Organizer
      World Congress on Medical Physics and Biomedical Engineering 2009 (WC 2009)
    • Place of Presentation
      Munich ICM, Munich, Germany.
    • Year and Date
      20090907-20090912
  • [Presentation] Selective Treatment of Atherosclerotic Plaques Using Nanosecond Pulsed Laser with a Wavelength of 5.75μm for Less-invasive Laser Angioplasty2009

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Organizer
      European Conference on Biomedical Optics (ECBO) 2009
    • Place of Presentation
      ICM, Munich, Germany.
    • Year and Date
      20090614-20090618
  • [Presentation] 波長5.75μmのナノ秒パルスレーザーによる低侵襲な血管形成術の開発2008

    • Author(s)
      石井克典, 月元秀樹, 間久直, 粟津邦男
    • Organizer
      第29回日本レーザー医学会総会
    • Place of Presentation
      東京工科大学八王子キャンパス,東京都八王子市
    • Year and Date
      20081115-20081116
  • [Book] 第16章生体分子振動領域での新しいレーザー診断・治療,次世代光医療-レーザー技術の臨床への橋渡し-(粟津邦男監修)2010

    • Author(s)
      石井克典, 粟津邦男
    • Total Pages
      171-183
    • Publisher
      シーエムシー出版

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Published: 2012-01-26   Modified: 2016-04-21  

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