2012 Fiscal Year Final Research Report
Molecular mechanisms for neuronal function via vesicular trafficking
| Project/Area Number |
20670003
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| Research Category |
Grant-in-Aid for Young Scientists (S)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | Kyushu University |
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Principal Investigator |
SHIRANE Michiko 九州大学, 生体防御医学研究所, 准教授 (90398082)
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| Project Period (FY) |
2008 – 2012
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| Keywords | 神経細胞 / 脳神経疾患 / 細胞内輸送 / プロトルーディン / FKBP38 |
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| Research Abstract |
The purpose of our study was to clarify the regulatory mechanism of intracellular transport in nervous system. Particularly, we aimed at the elucidation of the function of the molecular chaperon protein FKBP38 and the trafficking regulatory protein protrudin. As a result, we revealed the part of the causal mechanisms of neurological disorders such as Parkinson’s disease or hereditary spastic paraplegia.
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