2010 Fiscal Year Final Research Report
Development of degradable probes
| Project/Area Number |
20685012
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Chemistry related to living body
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SATO Moritoshi The University of Tokyo, 大学院・総合文化研究科, 准教授 (00323501)
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| Project Period (FY) |
2008 – 2010
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| Keywords | プローブ / 可視化 / キナーゼ / ユビキチン / タンパク質分解 |
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| Research Abstract |
Molecular imaging could be the most powerful technique for observing spatial and temporal dynamics of molecular processes in living cells and organisms, if probes for the relevant molecular processes become available. In the present study, we have developed degradable probes based on a new principle that allows imaging protein phosphorylation in living organisms.
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