2010 Fiscal Year Final Research Report
Molecular basis of interaction between virus and vector mosquito
| Project/Area Number |
20688013
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Obihiro University of Agriculture and Veterinary Medicine |
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Principal Investigator |
KANUKA Hirotaka 帯広畜産大学, 原虫病研究センター, 教授 (50342770)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 蚊 / ウイルス / RNA / 干渉 / 自然免疫 / 感染症 / 節足動物 |
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| Research Abstract |
Blood-sucking arthropods, including mosquitoes transmit numerous virus disease during blood feeding. Using a virus infection model in Drosophila and Aedes mosquito, we uncovered genetically encoded resistance of vector mosquito to virus infection as measured by the extent to which survival rate decreased via increasing virus burden. These results suggest that anti-virus responses of vector mosquito are not restricted to its survival but rather can be applied to capacity to employ virus mutualism during the disease transmission.
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