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2010 Fiscal Year Final Research Report

Multifaceted exploration of nonhomogeneous and ambiguous data by combining partial similarities

Research Project

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Project/Area Number 20700134
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Intelligent informatics
Research InstitutionKyoto University

Principal Investigator

TAKIGAWA Ichigaku  Kyoto University, 化学研究所, 助教 (10374597)

Project Period (FY) 2008 – 2010
Keywordsデータマイニング / 部分構造探索 / アルゴリズム / 機械学習
Research Abstract

Due to the computerization of industrial and scientific data, we can automatically collect or systematically obtain a huge dataset. Whereas these data are more easily accessible than before, their poor quality causes problems when we try to statistically analyze and utilize them. Many levels of information are collapsed into a single dataset since the purpose of use is ambiguous and unfixed in advance, and as a result, their quality is not sufficiently homogeneous. To address this problem, we developed novel statistical methods based on recently-emerged techniques for substructure enumeration, which can analyze those types of data by combining partial or local similarities in the data.

  • Research Products

    (19 results)

All 2011 2010 2009 2008 Other

All Journal Article (11 results) (of which Peer Reviewed: 10 results) Presentation (6 results) Remarks (2 results)

  • [Journal Article] ROS-DET : robust detector of switching mechanisms in gene expression2011

    • Author(s)
      M.Kayano, I.Takigawa, M.Shiga, K.Tsuda, H.Mamitsuka
    • Journal Title

      Nucleic Acids Research 印刷中

      Pages: doi : 10.1093/nar/gkr130

    • Peer Reviewed
  • [Journal Article] Efficiently mining delta-tolerance closed frequent subgraphs2011

    • Author(s)
      I.Takigawa, H.Mamitsuka
    • Journal Title

      Machine Learning Vol.82, No.

      Pages: 95-121

    • Peer Reviewed
  • [Journal Article] Mining significant substructure pairs for interpreting polypharmacology in drug-target network2011

    • Author(s)
      I.Takigawa, H.Mamitsuka
    • Journal Title

      PLoS One Vol.6, No.2

      Pages: e16999

    • Peer Reviewed
  • [Journal Article] A spectral approach to clustering numerical vectors as nodes in a network2011

    • Author(s)
      M.Shiga, I.Takigawa, H.Mamitsuka
    • Journal Title

      Pattern Recognition Vol.44, No.2

      Pages: 236-251

    • Peer Reviewed
  • [Journal Article] Mining metabolic pathways through gene expression2010

    • Author(s)
      T.Hancock, I.Takigawa, H.Mamitsuka
    • Journal Title

      Bioinformatics Vol.26, No.17

      Pages: 2128-2135

    • Peer Reviewed
  • [Journal Article] Algorithms for finding a minimum repetition representation of a string2010

    • Author(s)
      A.Nakamura, T.Saito, I.Takigawa, H.Mamitsuka, M.Kudo
    • Journal Title

      Lecture Notes in Computer Science Vol.6393

      Pages: 185-190

    • Peer Reviewed
  • [Journal Article] On the performance of methods for finding a switching mechanism in gene expression2010

    • Author(s)
      M.Kayano, I.Takigawa, M.Shiga, K.Tsuda, H.Mamitsuka
    • Journal Title

      Genome Informatics Vol.24

      Pages: 69-83

    • Peer Reviewed
  • [Journal Article] Mining patterns from glycan structures2010

    • Author(s)
      I.Takigawa, K.Hashimoto, M.Shiga, M.Kanehisa, H.Mamitsuka
    • Journal Title

      Proceedings of the International Beilstein Symposium on Glyco-Bioinformatics

      Pages: 13-24

  • [Journal Article] Convex sets as prototypes for classifying patterns2009

    • Author(s)
      I.Takigawa, M.Kudo, A.Nakamura
    • Journal Title

      Engineering Applications of Artificial Intelligence Vol.22, No.1

      Pages: 103-108

    • Peer Reviewed
  • [Journal Article] Efficiently finding genome-wide three-way gene interactions from transcript- and genotype-data2009

    • Author(s)
      M.Kayano, I.Takigawa, M.Shiga, K.Tsuda, H.Mamitsuka
    • Journal Title

      Bioinformatics Vol.25, No.21

      Pages: 2735-2743

    • Peer Reviewed
  • [Journal Article] Mining significant tree patterns in carbohydrate sugar chains2008

    • Author(s)
      H.Hashimoto, I.Takigawa, M.Shiga, M.Kanehisa, H.Mamitsuka
    • Journal Title

      Bioinformatics Vol.24, No.16

      Pages: i167-i173

    • Peer Reviewed
  • [Presentation] Mining significant substructure- substructure pairs in structural associations2009

    • Author(s)
      I.Takigawa, K.Tsuda, H.Mamitsuka
    • Organizer
      The 20th International Conference on Genome Informatics (GIW2009)
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      20091214-20091216
  • [Presentation] Genome-wide three-way gene interactions from transcript and genotype data2009

    • Author(s)
      M.Kayano, I.Takigawa, M.Shiga, K.Tsuda, H.Mamitsuka
    • Organizer
      The 20th International Conference on Genome Informatics (GIW2009)
    • Place of Presentation
      Yokohama, Japan
    • Year and Date
      20091214-20091216
  • [Presentation] Efficiently finding significant substructural patterns conserved in glycans2008

    • Author(s)
      I.Takigawa, K.Hashimoto, M.Shiga, M.Kanehisa, H.Mamitsuka
    • Organizer
      2008 Annual conference of the Japanese Society for Bioinformatics
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      20081215-20081216
  • [Presentation] Classification by reflective convex hulls2008

    • Author(s)
      M.Kudo, I.Takigawa, A.Nakamura
    • Organizer
      19th International conference on pattern recognition (ICPR2008)
    • Place of Presentation
      Tampa, Florida, USA
    • Year and Date
      20081208-20081211
  • [Presentation] Mining significant tree patterns in carbohydrate sugar chains2008

    • Author(s)
      K.Hashimoto, I.Takigawa, M.Shiga, M.Kanehisa, H.Mamitsuka
    • Organizer
      ECCB'08 European Conference on Computational Biology
    • Place of Presentation
      Cagliari, Italy
    • Year and Date
      20080922-20080926
  • [Presentation] 酵素遺伝子の発現情報に基づく効率的な代謝経路ランキング2008

    • Author(s)
      瀧川一学
    • Organizer
      2008年度統計関連学会連合大会
    • Place of Presentation
      慶應義塾大学
    • Year and Date
      20080907-20080910
  • [Remarks] プロジェクトホームページ

    • URL

      http://www.bic.kyoto-u.ac.jp/pathway/grasp/

  • [Remarks]

    • URL

      http://www.bic.kyoto-u.ac.jp/pathway/kayano/bioinfo_three-way.html

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Published: 2012-02-13   Modified: 2016-04-21  

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