development and assessment of a scan statistic for detecting disease clustering

2009 Fiscal Year Final Research Report

• Project/Area Number: 20700262
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Statistical science
• Research Institution: National Institute of Public Health
• Principal Investigator: TAKAHASHI Kunchiko National Institute of Public Health, 技術評価部, 研究員 (50323259)
• Project Period (FY): 2008 – 2009
• Keywords: 空間統計学 / 空間疫学 / スキャン統計量 / 疾病集積性

Research Abstract

In spatial epidemiology, clustering test based on a scan statistic is used for detecting disease clusters. We aimed at proposing a new test statistic which can detect the clusters more accurate than conventional statistics. We proposed a new space-time scan statistic which implements an outbreak model to capture localized emerging disease outbreaks more timely and correctly, and our illustrations and simulations showed that the proposed statistic is well suited for detecting disease outbreaks.

Research Products

• [Journal Article] ベイズ推定の医療費地域差指数への適用 (2010)
  • Author(s): 高橋邦彦, 飛田英祐, 山岡和枝, 丹後俊郎
  • Journal Title: 日本公衆衛生雑誌 57(1) Pages: 17-26
  • Peer Reviewed
• [Journal Article] A space-time scan statistic for detecting emerging outbreaks (2010)
  • Author(s): Tango T, Takahashi K, Kohriyama K
  • Journal Title: Biometrics (印刷中)
  • Peer Reviewed
• [Journal Article] A flexibly shaped space-time scan statistic for disease outbreak detection and monitoring (2008)
  • Author(s): Takahashi K, Kulldorff M, Tango T, Yih K
  • Journal Title: International Journal of Health Geographies 7 Pages: 14
  • Peer Reviewed
• [Journal Article] Spatial clusters of Creutzfeldt-Jakob disease mortality in Japan between 1995 and 2004 (2008)
  • Author(s): Doi Y, Yokoyama T, Sakai M, Nakamura Y, Tango T, Takahashi K
  • Journal Title: Neuroepidemiology 30 Pages: 222-228
  • Peer Reviewed
• [Journal Article] 疾病地図から疾病集積性へ (2008)
  • Author(s): 高橋邦彦, 横山徹爾, 丹後俊郎
  • Journal Title: 保健医療科学 57(2) Pages: 86-92
  • Peer Reviewed
• [Journal Article] 疾病集積性の検定を用いた症候サーベイランス解析 (2008)
  • Author(s): 高橋邦彦, 丹後俊郎
  • Journal Title: 保健医療科学 57(2) Pages: 122-129
  • Peer Reviewed
• [Presentation] Geographical clustering of caries prevalence on 3-year-old children in Hokkaido (2010)
  • Author(s): Aida J, Takahashi K, Yamaoka K, Tango T, Akino K, Osaka K.
  • Organizer: 国際疫学会西太平洋地域学術会議兼第20回日本疫学会学術総会
  • Place of Presentation: 埼玉県立大学
  • Year and Date: 20100100
• [Presentation] Flexible and circular ILI clusters during H1N1 Investigation in NYC (2009)
  • Author(s): Goranson C, Konty K, Takahashi K, Paladini M.
  • Organizer: Eighth Annual International Society for Disease Surveillance Conference
  • Place of Presentation: Miami, FL, USA
  • Year and Date: 20091200
• [Presentation] 新型インフルエンザ発生動向に係る統計的諸問題～データ収集から統計的推測へ～ (2009)
  • Author(s): 高橋邦彦
  • Organizer: 日本計算機統計学会第23回シンポジウム特別講演
  • Place of Presentation: 札幌学院大
  • Year and Date: 20091100
• [Presentation] Pathway-based scan analysis of genome-wide association data (2009)
  • Author(s): Nishiyama T, Takahashi K, Tango T, Kishino H.
  • Organizer: The American Society of Human Genetics 59th Annual Meeting
  • Place of Presentation: Honolulu, Hawaii
  • Year and Date: 20091000
• [Presentation] 医療費における地域差指数のベイズ推定 (2009)
  • Author(s): 高橋邦彦, 飛田英祐, 山岡和枝, 丹後俊郎.
  • Organizer: 第68回日本公衆衛生学会総会
  • Place of Presentation: 奈良市
  • Year and Date: 20091000
• [Presentation] ゲノムワイド関連研究データに対する遺伝子パスウェイに基づくスキャン解析. 日本人類遺伝学会 (2009)
  • Author(s): 西山毅, 高橋邦彦, 丹後俊郎, 岸野洋久
  • Organizer: 第54回大会
  • Place of Presentation: グランドプリンスホテル高輪
  • Year and Date: 20090900
• [Presentation] 感染症疫学と症候サーベイランスへの疾病集積性検定の応用 (2009)
  • Author(s): 高橋邦彦, 丹後俊郎
  • Organizer: 2009年度統計関連学会連合大会企画セッション「感染症対策における計量生物学の貢献」
  • Place of Presentation: 同志社大学
  • Year and Date: 20090900
• [Presentation] Parkinson disease mortality in Japan, 1995-2004: Analysis of clustering (2009)
  • Author(s): Doi Y, Yokoyama T, Takahashi K, Tango T.
  • Organizer: The First International Congress on Clinical Neurology and Epidemiology
  • Place of Presentation: Munich
  • Year and Date: 20090800
• [Presentation] 劇症肝炎による死亡の地域集積性に関する検討 (2009)
  • Author(s): 土井由利子, 横山徹爾, 酒井美良, 高橋邦彦, 丹後俊郎
  • Organizer: 第19回日本疫学会学術総会
  • Place of Presentation: 金沢市
  • Year and Date: 20090100
• [Presentation] A comparison of SaTScan and FleXScan for outbreak detection and monitoring (2008)
  • Author(s): Takahashi K, Tango T.
  • Organizer: The 7th Annual International Society for Disease Surveillance Conference
  • Place of Presentation: Raleigh, North Carolina, USA
  • Year and Date: 20081200
• [Presentation] A new space-time scan statistic for timely outbreak detection taking overdispersion into account (2008)
  • Author(s): Tango T, Takahashi K.
  • Organizer: The 7th Annual International Society for Disease Surveillance Conference
  • Place of Presentation: Raleigh, North Carolina, USA
  • Year and Date: 20081200
• [Presentation] Cluster detection comparison in syndromic surveillance (2008)
  • Author(s): Goranson C, Takahashi K, Tango T, Cajigal A, Paladini M, Murray EL, Nguyen T, Konty K, Hardisty F.
  • Organizer: The 7th Annual International Society for Disease Surveillance Conference
  • Place of Presentation: Raleigh, North Carolina, USA.
  • Year and Date: 20081200