2009 Fiscal Year Final Research Report
Systems evolutionary analysis on Hox transcription networks in the early embryonic development
| Project/Area Number |
20700266
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Bioinformatics/Life informatics
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
OGISHIMA Soichi Tokyo Medical and Dental University, 難治疾患研究所, 助教 (40447496)
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| Project Period (FY) |
2008 – 2009
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| Research Abstract |
We identified Hox transcriptional networks which have key roles in regulating the patterning of the antero-posterior axis at phylotypic stage in a metazoan embryo. We conducted bioinformatics methods including promoter analysis on Hox regulating genes in each evolutionary stage and anatomical structure which were retrieved from public gene expression database. We then compared Hox transcriptional networks among mouse, sea squirt, and fruit fly.
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