2011 Fiscal Year Final Research Report
Theory of memory transfer and consolidation in motor learning
| Project/Area Number |
20700301
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
YAMAZAKI Tadashi 独立行政法人理化学研究所, 戦略ユニット, 研究員 (40392162)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 小脳 / 運動学習 / 視機性眼球運動 / ゲイン適応 / 記憶の固定化 / モデル / シミュレーション |
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| Research Abstract |
To understand the neural mechanism of memory transfer phenomenon found in cerebellar motor learning, we built a large-scale computational model of the cerebellum for gain adaptataion of optokinetic response eye movments, which is used as an experimental paradigm for memory transfer phenomenon. We published a paper in an international journal. We studied the learning rule for mossy fiber-vestibular nuclear cell synapses to demonstrate robust memory transfer phenomenon, and found that Bienenstock-Cooper-Munro(BCM) rule is a candidate. We also reported that BCM rule is sufficient to reproduce the spacing effect in motor learning.
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