2010 Fiscal Year Final Research Report
Detailed estimation of local circuit structure based on spike time reliability of cortical neurons
| Project/Area Number |
20700304
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | The Institute of Physical and Chemical Research |
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Principal Investigator |
TERAMAE Junnosuke The Institute of Physical and Chemical Research, 脳回路機能理論研究チーム, 副チームリーダー (50384722)
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| Project Period (FY) |
2008 – 2010
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| Keywords | リミットサイクル / 確率過程 / ノイズ / スパイク / 発火率 / 対数正規分布 / ネットワーク |
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| Research Abstract |
Isolated cortical neurons have known to respond to fluctuating inputs with high temporal precision about few milliseconds. The reliable responses of neurons, however, may be influenced local network structure in cortex. Here, we provided theories which clarify relationship between response reliability of neurons and potential factors including network structure, intrinsic properties of neurons, EPSP (excitatory-postsynaptic potentiation) distribution, and statistics of input signals. We have also reveals possible generation mechanism of fluctuating input to cortical neurons and computational role of them.
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