2010 Fiscal Year Final Research Report
Monitoring of CREB phosphorylation in single live neuron using split luciferase
| Project/Area Number |
20700331
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | University of Toyama |
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Principal Investigator |
ISHIMOTO Tetsuya University of Toyama, 大学院・医学薬学研究部(医学), 助教 (40397170)
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| Project Period (FY) |
2008 – 2010
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| Keywords | CREB / リン酸化 / ルシフェラーゼ |
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| Research Abstract |
cAMP response element binding protein (CREB) is a transcription factor which is activated by phosphorylation. We developed probe proteins that detected CREB phosphorylation using bioluminescence. In addition to the 1-molecule-type probe that was planned at the beginning of the project, we made 2-molecule-type probes. This approach increased the specificity of the probes.
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Research Products
(11 results)
