2009 Fiscal Year Final Research Report
Analysis of mouse higher-order visual cortex by differential imaging
| Project/Area Number |
20700347
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurophysiology and muscle physiology
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| Research Institution | Niigata University |
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Principal Investigator |
TOHMI Manavu Niigata University, 脳研究所, 助教 (10401770)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 高次視覚領域 / フラビン蛍光イメージング / 差分イメージング / 経験依存的可塑性 / in vivo / プロトカドヘリン / ノックアウトマウス / スライス |
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| Research Abstract |
It became possible to separate and to identify mouse's several higher-order visual areas by the combination with the pattern stimulus having different speed with flavin fluorescent imaging. Therefore the high order visual areas which were difficult to study until that time were observed. The properties of neurons in each area were different in the directional selectivity and the preferred stimulation speed. The property was disturbed in the animal that had bred under the flash light condition. Moreover, the anatomical combinations of each region were observed using with neural traser. Finally, abnormality was discovered in the property of the higher-order visual areas in the knockout mouse of cell-adhesion molecule CNR.
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