2009 Fiscal Year Final Research Report
Mechanical effect on bone mineralization and microstructure in cortex
| Project/Area Number |
20700378
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Niigata University |
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Principal Investigator |
YAMAKO Go Niigata University, ベンチャー・ビジネス・ラボラトリー, VBL研究機関研究員 (50452074)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 生体力学 / 機械材料・材料力学 / 生体材料 |
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| Research Abstract |
Osteoporotic femoral neck fracture is associated with the change in bone mechanical properties that are determined by the tissue mineral density and micro-porous structure. To estimate bone fragility by osteoporosis non-invasively, we quantified the tissue mineral density and porous structure in the femoral cortex of patients with total hip arthroplasty, using a polychromatic micro CT system with K2HPO4 phantom. Our results showed that bone mineral density distribution could assume to be homogeneous, and indicated the importance of the porosity on the mechanical properties of cortical bone.
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