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2008 Fiscal Year Final Research Report

Bone fatigue damage under single, static, and cyclic loading : Implications for fatigue fracture etiology.

Research Project

  • PDF
Project/Area Number 20700387
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biomedical engineering/Biological material science
Research InstitutionKinki University

Principal Investigator

YAMAMOTO Ei  Kinki University, 生物理工学部, 准教授 (00309270)

Project Period (FY) 2008 – 2009
Keywordsバイオメカニクス
Research Abstract

In the present study, the specimens were obtained from the middiaphysis of bovine femur. We applied the overloads to the specimens singly, cyclically, or statically. Microdamage in bone tissues induced by overloading was observed by a fluorescence microscopy. The growth of microdamage was monitored during the course of mechanical loading tests by the application of a series of fluorescent chelating agents. By sectioning the specimens both transversely and longitudinally, we examined the damage size and monitored how this changes during mechanical loading. Fluorescence microscopic images showed the propagating of microdamage which is labeled with different agents. Both in the transverse and longitudinal directions, microdamage was found to be greater in case of static and cyclic overloading in comparison to that of single overloading. Not only linear microcracks but also diffused microdamage were observed in the all specimens applied to overloading. The linear microcracks and diffused microdamage were dominated in the cyclic-overload and static-overload groups, respectively. These results showed that the bone microdamage accumulation strongly depends on the cycles, durations, and modes of non-destructive compressive overloading. If the damage accumulation at each type of overloading occurs at such a rate that the capacity for bone repair is exceeded, stress fractures may result in bone tissues.

  • Research Products

    (4 results)

All 2010 2009 2008

All Presentation (4 results)

  • [Presentation] 圧縮過負荷下で皮質骨に生じる微小損傷の形態評価2010

    • Author(s)
      松本祐樹, 山本衛
    • Organizer
      日本機械学会第22回バイオエンジニアリング講演会講演論文集
    • Place of Presentation
      岡山
    • Year and Date
      2010-01-09
  • [Presentation] 骨組織に発生した微小損傷の蛍光顕微鏡観察2009

    • Author(s)
      山本衛, 松本祐樹, 中山裕隆
    • Organizer
      日本非破壊検査協会平成21年春季大会講演概要集
    • Place of Presentation
      東京
    • Year and Date
      2009-05-20
  • [Presentation] 繰り返し圧縮負荷を作用させた皮質骨で発生する微小損傷の蓄積2009

    • Author(s)
      山本衛, 松本祐樹, 中山裕隆
    • Organizer
      日本機械学会第21回バイオエンジニアリング講演会講演論文集
    • Place of Presentation
      札幌
    • Year and Date
      2009-01-23
  • [Presentation] 非破壊的応力下で皮質骨に発生する微小損傷の経時的変化2008

    • Author(s)
      松本祐樹, 山本衛
    • Organizer
      日本機械学会第19回バイオフロンティア講演会講演論文集
    • Place of Presentation
      八王子
    • Year and Date
      2008-09-25

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Published: 2011-06-18   Modified: 2016-04-21  

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