2009 Fiscal Year Final Research Report
Distribution and development of the proton-gated ion channel in respiratory system
| Project/Area Number |
20700429
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
KIKUCHI Shin Sapporo Medical University, 医学部, 助教 (20404585)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ASIC2 / 線毛 / 呼吸器 / 発生 |
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| Research Abstract |
Acid sensing ion channel 2 (ASIC2) is a member of epithelial sodium channels and works in low pH. Our study revealed that ASIC2 expressed at respiratory cilia and the expression was observed during fetus period in rat. These results suggested that respiratory ciliated cells had ability to sense an acidic environment in airway from the birth.
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[Journal Article] Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro.2008
Author(s)
Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, Kurose M, Koizumi J, Kamekura R, Murata M, Tanaka S, Chiba H, Himi T, Sawada N
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Journal Title
J. Mol. Histol 39
Pages: 265-273
Peer Reviewed
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