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2010 Fiscal Year Final Research Report

Anti-fatigue effects of intrinsic motivation using non-invasive functional neuroimaging

Research Project

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Project/Area Number 20700541
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Applied health science
Research InstitutionOsaka City University

Principal Investigator

MIZUNO Kei  Osaka City University, 大学院・医学研究科, 研究員 (60464616)

Project Period (FY) 2008 – 2010
Keywords心身の健康 / 疲労 / 意欲 / 内発的意欲 / パフォーマンス
Research Abstract

Fatigue sensation was attenuated by an intrinsic reward (IR) during a fatigue-inducing tasks. Functional magnetic resonance imaging revealed that the brain regions involved in the IR were ventral striatum (VS) and anterior cingulate cortex (ACC) during the fatigue-inducing tasks. In addition, the activations of the VS and ACC were correlated with motivation score and score for the alleviation of fatigue sensation as derived from a questionnaire, respectively. These results suggest that anti-fatigue effects of intrinsic motivation are associated with the responsiveness of the ACC.

  • Research Products

    (15 results)

All 2010 2009 2008

All Journal Article (6 results) (of which Peer Reviewed: 6 results) Presentation (5 results) Book (4 results)

  • [Journal Article] Personality and fatigue in medical students.2010

    • Author(s)
      Tanaka, M., Mizuno, K., Fukuda, S., Watanabe, Y.
    • Journal Title

      Psychological Reports 106(2)

      Pages: 567-575

    • Peer Reviewed
  • [Journal Article] Central nervous system fatigue alters autonomic nerve activity.2009

    • Author(s)
      Tanaka, M., Mizuno, K., Tajima, S., Sasabe, T., Watanabe, Y.
    • Journal Title

      Life Sciences 84(7-8)

      Pages: 233-299

    • Peer Reviewed
  • [Journal Article] Personality traits associated with intrinsic academic motivation in medical students.2009

    • Author(s)
      Tanaka, M., Mizuno, K., Fukuda, S., Shigihara, Y., Tajima, S., Watanabe, Y.
    • Journal Title

      Medical Education 43(4)

      Pages: 384-387

    • Peer Reviewed
  • [Journal Article] Stress and coping style are associated with severe fatigue in medical students.2009

    • Author(s)
      Tanaka, M., Fukuda, S., Mizuno, K., Kuratsune, H., Watanabe, Y.
    • Journal Title

      Behavioral Medicine 35(3)

      Pages: 87-92

    • Peer Reviewed
  • [Journal Article] Strategies specifically designed for supporting the academic motivation of individual college students.2008

    • Author(s)
      Yoshida, M., Tanaka, M., Mizuno, K., Ishii, A., Nozaki, K., Urakawa, A., Cho, Y., Kataoka, Y., Watanabe, Y.
    • Journal Title

      International Journal of Neuroscience 118(10)

      Pages: 1400-1411

    • Peer Reviewed
  • [Journal Article] The neural basis of academic achievement motivation.2008

    • Author(s)
      Mizuno, K., Tanaka, M., Ishii, A., Tanabe, C. H., Onoe, H., Sadato, N., Watanabe, Y.
    • Journal Title

      NeuroImage 42(1)

      Pages: 369-378

    • Peer Reviewed
  • [Presentation] Interdisciplinary research of neuroscience and education for elucidating the neural mechanisms of fatigue and motivation to learn in children and adolescents.2010

    • Author(s)
      Mizuno, K., Tanaka, M., Miike, T., Imai-Matsumura, K., Sadato, N. Watanabe, Y
    • Organizer
      The 16th Takeda Science Foundation Symposium on Bioscience "Casting light on life"
    • Place of Presentation
      Tokyo, Japan
    • Year and Date
      2010-12-01
  • [Presentation] Neurological relationship between divided attention and motivation : an fMRI study.2010

    • Author(s)
      Mizuno, K., Tanabe, C.H., Tanaka, M., Sadato, N. Watanabe, Y
    • Organizer
      The 33th Annual Meeting of the Japan Neuroscience Society (Neuro 2010)
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2010-09-03
  • [Presentation] Investigation of neural substrates associated with fatigue and motivation using functional neuroimaging.2010

    • Author(s)
      Mizuno, K.
    • Organizer
      The Thirteenth Conference of Peace through Mind/Brain Science
    • Place of Presentation
      Hamamatsu, Japan
    • Year and Date
      2010-02-23
  • [Presentation] Neural substrates of motivation to learn and fatigue sensation.2008

    • Author(s)
      Mizuno, K., Tanaka, M., Tajima, S., Tanabe, C.H., Kataoka, Y., Onoe, H., Sadato, N., Watanabe, Y.
    • Organizer
      The 2008 World Molecular Imaging Congress
    • Place of Presentation
      Nice, France
    • Year and Date
      2008-09-12
  • [Presentation] Neural substrates of academic achievement motivation related to neural mechanism of fatigue.2008

    • Author(s)
      Mizuno, K., Tanaka, M., Tanabe, C.H., Onoe, H., Sadato, N., Watanabe, Y.
    • Organizer
      International Conference on Fatigue Science 2008
    • Place of Presentation
      Okinawa, Japan
    • Year and Date
      2008-09-05
  • [Book] 最新・疲労の科学 -日本初:抗疲労・抗過労への提言(疲労による作業能率低下の解析.医学のあゆみ)228(6)2009

    • Author(s)
      水野敬
    • Total Pages
      654-658
    • Publisher
      医歯薬出版株式会社
  • [Book] 現代化学「特集 疲労の科学」(疲れはどこで感じるのか?-脳機能イメージングを用いた疲れの脳科学-)2008

    • Author(s)
      水野敬, 渡辺恭良
    • Total Pages
      30-33
    • Publisher
      東京化学同人社
  • [Book] 精神医学[疲労と精神障害(ストレス-疲労-精神障害について)](疲労の脳内機序(Brain Dysfunction in Fatigue and Chronic Fatigue))50(6)2008

    • Author(s)
      渡辺恭良, 田中雅彰, 水野敬
    • Total Pages
      527-532
    • Publisher
      医学書院
  • [Book] Utility of an advanced trail making test as a neuropsychological tool for an objective evaluation of work efficiency during mental fatigue.(Fatigue Science for Human Health)(Watanabe, Y., Evengard, B., Natelson, B. H., Jason, L. A., Kuratsune, H.)2008

    • Author(s)
      Mizuno, K., Watanabe, Y.
    • Total Pages
      47-54
    • Publisher
      Springer

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Published: 2012-02-13   Modified: 2016-04-21  

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