2009 Fiscal Year Final Research Report
Elucidation of lipid metabolic disorder and liver injury on the high fat diet
| Project/Area Number |
20700603
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Eating habits, studies on eating habits
|
|---|
| Research Institution | Kinjo Gakuin University |
|---|
Principal Investigator |
KITAMORI Kazuya Kinjo Gakuin University, 生活環境学部, 講師 (80387597)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | NAFLD / NASH / 高脂肪食 |
|---|
| Research Abstract |
Patients with nonalcoholic fatty liver disease (NAFLD) are increasing worldwide, and preventive measures are an urgent need and primary concern today. The purpose of this study is to develop and clarify the usefulness of the SHRSP5/Dmcr rat as an animal model for human NAFLD. We have developed animal model of the NAFLD progression as observed in humans using SHRSP5/Dmcr rats fed an HFC diet. This model appears to be useful to investigate the mechanism of human NAFLD progression.
|
