2009 Fiscal Year Final Research Report
Role of Rev1, repair enzyme in translesion DNA synthesis, in tumorigenesis
| Project/Area Number |
20710043
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Hiroshima University |
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Principal Investigator |
TOYOSHIMA Megumi Hiroshima University, 原爆放射線医科学研究所, 助教 (80423052)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 生物影響 / 修復 |
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| Research Abstract |
Over-expression of Rev1 may be accelerate development of chemical induced tumors. Furthermore, over-expression of Rev1 induced the point mutation at the specific locus which was not detected in the wild-type mice.
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[Journal Article] Levels of N-acylethanolamines in O, O, S- rimethylphosphorothioate (OOS-TMP)- treated C57BL/6J mice and potential anti-obesity, anti-diabetic effects of OOS-TMP in hyperphagia and hyperglycemia mouse models2009
Author(s)
Huang L, Toyoshima M, Asakawa A, Inoue K, Harada K, Kinoshita T, Chen S, Koizumi A
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Journal Title
Pharmacol Biochem Behav 92(1)
Pages: 1-5
Peer Reviewed
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