2009 Fiscal Year Final Research Report
The binding mechanism of endocrine disruptors to protein disulfide isomerase and its physiological effects.
| Project/Area Number |
20710054
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Kwansei Gakuin University |
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Principal Investigator |
OKADA Kazushi Kwansei Gakuin University, 理工学研究科, 博士研究員 (40423892)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 内分泌かく乱物質 |
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| Research Abstract |
We investigated the S-nitrosylation of PDI by bisphenol A in GH3 cells. S-nitrosylated PDI (SNO-PDI) was increased by 24h-treatment of bisphenol A in the presence of T_3, although not increased by T_3 only.
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