2010 Fiscal Year Final Research Report
Mechanistic Study of Cell Death by Using Cell Death Control Molecules
| Project/Area Number |
20710163
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Living organism molecular science
|
|---|
| Research Institution | The Institute of Physical and Chemical Research |
|---|
Principal Investigator |
DODO Kosuke The Institute of Physical and Chemical Research, 袖岡有機合成化学研究室, 研究員 (20415243)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Keywords | 細胞死 / アポトーシス / ネクローシス / ケミカルバイオロジー / 創薬科学 / ミトコンドリア |
|---|
| Research Abstract |
Cell death is one of the most important systems for the maintenance of multicellular organisms. In this study, we performed the development and mechanistic study of cell death control molecules, i.e., inhibitors or inducers of cell death. As a result, we obtained some cell death inducers having unique cell death inducing properties. By using these compounds and modified probes, we determined some binding proteins as potent candidates of target molecules.
|
