2009 Fiscal Year Final Research Report

Microwave-assisted rapid fabrication of high performance monolithic capillary column

Research Project

Project/Area Number	20750058
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Analytical chemistry
Research Institution	Gifu University
Principal Investigator	LIM Leewah Gifu University, 工学部, 助教 (80377689)
Project Period (FY)	2008 – 2009
Keywords	モノリス型キャピラリーカラム / マイクロ波 / 迅速調製 / 液体クロマトグラフィー
Research Abstract	Rapid fabrication of monolithic silica- and polymer-based capillary columns were evaluated using microwave irradiation. The reaction solution was filled into fused-silica capillary tubing and the column was then irradiated at different time under various temperature and output control of the microwave device. The morphology of the monoliths was also observed with a scanning electron microscope (SEM) and was compared to those monoliths that were fabricated under conventional conditions. As the results, as for the silica-based monolith, high performance capillary column was obtained when the column was irradiated at output 300 W for 1 h during the sol-gel reaction, which was normally carried out for 24 h. As for the polymer-based monolith, radiation output at 200W for 15 min was enough to make a relatively high performance capillary column for normal liquid chromatographic separation.