2009 Fiscal Year Final Research Report
Development of New Oxidation Reactions to Innovate Synthetic Strategies
| Project/Area Number |
20750070
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Synthetic chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KAMIJO Shin The University of Tokyo, 大学院・薬学系研究科, 助教 (00359548)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 酸化 / 光反応 / C-H結合活性化 / 触媒反応 / 合成反応 |
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| Research Abstract |
We have developed the following reactions for a direct introduction of oxygen functionality on carbon skeletons. (1)Mn-catalyzed unified oxidation of ethers, benzylic compounds, and alcohols. (2)Direct ether oxidation using mCPBA/CCl3CN reagent system. (3)Intramolecular C-H hydroxylation using dioxirane as an oxidizing agent. For an introduction of carbon functionality on carbocycles, we have developed acylation via two-step sequence including a photocyclization.
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