2009 Fiscal Year Final Research Report
Development of Molecular Transformation Method Based on Transition-Metal-Catalyzed Reaction Involving Hydrogen-Boron Exchange
| Project/Area Number |
20750076
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Kyoto University |
|---|
Principal Investigator |
OHMURA Toshimichi Kyoto University, 工学研究科, 講師 (00378803)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | 遷移金属触媒 / 立体選択的合成 / カスケード反応 / 官能基化 / 有機ホウ素化合物 / 有機ケイ素化合物 |
|---|
| Research Abstract |
An efficient platinum-catalyzed reaction involving hydrogen-boron exchange on the carbon-carbon double bond has been established, which results in regioand stereoselective construction of organoboron compounds. A rhodium-catalyzed addition reaction of hydrosilane, which is formed in the hydrogen-boron exchange, to the carbon-carbon double bond has also been developed. Finally, sequential molecular transformation involving stereoselective construction of both carbon-carbon double bond and stereogenic carbon centers has been achieved by applying those two reactions.
|
