2009 Fiscal Year Final Research Report
Study on imaging system for analysis of endothelial vascular function
| Project/Area Number |
20760264
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Measurement engineering
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| Research Institution | Tokyo University of Agriculture and Technology |
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Principal Investigator |
NISHIDATE Izumi Tokyo University of Agriculture and Technology, 大学院・共生科学技術研究院, 講師 (70375319)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 皮膚血流 / 血管拡張性 / 動脈血流入量 / 静脈容量 / 反応性充血 / 皮膚画像計測 |
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| Research Abstract |
To visualize the human skin hemodynamics, we investigated a method that is specifically developed for estimating the concentrations of oxygenated and deoxygenated blood in skin tissue from RGB digital color images. Monte Carlo simulation of light transport in skin tissue specifies a relation between the chromophore concentrations and the RGB-values. The total blood concentration can also be reconstructed. In vivo imaging of the total blood concentration was performed for 13 subjects during the upper limb occlusion at 50 and 250 mmHg-pressures, together with the strain-gauge plethysmograph (SPG). The arterial inflow, the venous capacitance, and time constant of venous outflow in skin tissue were calculated from the increase rate and the change of the total blood concentration. We confirmed that the arterial inflow, venous capacitance, and time constant of venous outfow in skin tissue obtained from the method correlate closely with those of limb measured by SPG.
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