2009 Fiscal Year Final Research Report
Mechanism for the stabilization of copper-containing methane monooxygenase by the protein complex formation
| Project/Area Number |
20760527
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Catalyst/Resource chemical process
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
MIYAJI Akimitsu Tokyo Institute of Technology, 大学院・総合理工学研究科, 助教 (40452023)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 酵素反応 / 天然ガス / 触媒・化学プロセス / メタノール合成 |
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| Research Abstract |
The mechanism for the stabilization of copper-containing methane monooxygenase (pMMO) by the formation of protein complex with methanol dehydrogenase (MDH) was elucidated. MDH protects the copper center of pMMO, which accepts electrons from the electron donor for pMMO, from hydrogen peroxide inhibiting pMMO, due to the binding of MDH to pMMO.
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