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2009 Fiscal Year Final Research Report

Understanding of cellular function of compatible solutes utilizing a synthetic approach

Research Project

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Project/Area Number 20760544
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Biofunction/Bioprocess
Research InstitutionKonan University

Principal Investigator

KOUMOTO Kazuya  Konan University, フロンティアサイエンス学部・生命化学科, 准教授 (60388759)

Project Period (FY) 2008 – 2009
Keywords生物機能工学
Research Abstract

It is becoming clear that certain metabolites play significant roles in participating in important cellular functions. In order to clarify their cellular function, applicant synthesized metabolite mimics and investigated the functions by mixing them with various biomolecules. As a result, synthetic metabolites possessing certain chemical structures showed profound effect on the stabilization and activation of cellular biomolecules.

  • Research Products

    (13 results)

All 2010 2009 2008

All Journal Article (1 results) Presentation (10 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Enhanced amplification of polymerase chain reaction by addition of cosolutes derived from a cellular compatible solute2008

    • Author(s)
      K. Koumoto, H. Ochiai, N. Sugimoto
    • Journal Title

      Nucleic Acids Symp. Ser. 52巻

      Pages: 257-258

  • [Presentation] 細胞内代謝産物を基体とする酵素活性化剤2010

    • Author(s)
      甲元一也
    • Organizer
      関西6私大新技術説明会
    • Place of Presentation
      東京(口頭発表)
    • Year and Date
      2010-02-26
  • [Presentation] 合成ライブラリーを用いた細胞内代謝産物群が酵素活性に及ぼす影響の解明2010

    • Author(s)
      甲元一也、出口瑛介
    • Organizer
      第12回生命化学研究会
    • Place of Presentation
      福井(ポスター発表)
    • Year and Date
      2010-01-08
  • [Presentation] 有機合成的手法を用いた代謝産物群のα-グルコシダーゼ活性化メカニズムの解明2009

    • Author(s)
      出口瑛介、甲元一也
    • Organizer
      生体機能関連化学若手の会第21回サマースクール
    • Place of Presentation
      京都(ポスター発表)
    • Year and Date
      20090713-20090714
  • [Presentation] 対イオン構造を有する合成代謝産物ライブラリーの創製2009

    • Author(s)
      出口瑛介、甲元一也
    • Organizer
      第29回有機合成若手セミナー
    • Place of Presentation
      神戸(ポスター発表)
    • Year and Date
      2009-11-24
  • [Presentation] Function of cellular metabolites for enzymatic reactions2009

    • Author(s)
      Kazuya Koumoto
    • Organizer
      Special Seminar 2 (BK21) in Gyoengsang National University
    • Place of Presentation
      Jinju, S. Korea
    • Year and Date
      2009-11-20
  • [Presentation] Function of cellular metabolites for enzymatic reactions2009

    • Author(s)
      Kazuya Koumoto
    • Organizer
      Special Seminar 1 (BK21) in Gyoengsang National University
    • Place of Presentation
      Jinju, S. Korea
    • Year and Date
      2009-11-19
  • [Presentation] 細胞内代謝産物がポリメラーゼ連鎖反応を補助、促進する2009

    • Author(s)
      甲元一也
    • Organizer
      知財ビジネスマッチングフェア2009
    • Place of Presentation
      大阪(口頭発表)
    • Year and Date
      2009-10-21
  • [Presentation] NanoBioNow(22)適合溶質のα-グルコシダーゼ活性に及ぼす影響2009

    • Author(s)
      出口瑛介、甲元一也、杉本直己
    • Organizer
      日本化学会第89春季年会
    • Place of Presentation
      船橋(口頭発表)
    • Year and Date
      2009-03-27
  • [Presentation] Enhanced amplification of polymerase chain reaction by addition of cosolutes derived from a cellular compatible solute2008

    • Author(s)
      K. Koumoto, H. Ochiai, N. Sugimoto
    • Organizer
      Joint Symposium of 18th International Roundtable on Nucleosides, nucleotides and Nucleic Acids and 35th International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      京都(ポスター発表)
    • Year and Date
      2008-09-09
  • [Presentation] Design of functional additives for the facilitation of polymerase chain reaction2008

    • Author(s)
      K. Koumoto
    • Organizer
      FIBER International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      神戸
    • Year and Date
      2008-09-07
  • [Patent(Industrial Property Rights)] 酵素活性を向上させるための組成物およびその利用2010

    • Inventor(s)
      甲元一也、出口瑛介
    • Industrial Property Rights Holder
      学校法人甲南学園
    • Industrial Property Number
      特許(優先権出願)・特願2010-001986
    • Filing Date
      2010-01-07
  • [Patent(Industrial Property Rights)] 酵素活性を向上させるための組成物およびその利用2009

    • Inventor(s)
      甲元一也、出口瑛介
    • Industrial Property Rights Holder
      学校法人甲南学園
    • Industrial Property Number
      特許・特願2009-46946
    • Filing Date
      2009-02-27

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Published: 2011-06-18   Modified: 2016-04-21  

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