2009 Fiscal Year Final Research Report
Structural analysis of pore forming CEL-III complex.
| Project/Area Number |
20770088
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Structural biochemistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
UNNO Hideaki Nagasaki University, 工学部, 助教 (10452872)
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| Project Period (FY) |
2008 – 2009
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| Keywords | CEL-III / 結晶構造解析 / PFT |
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| Research Abstract |
For structural analysis of pore forming CEL-III complex, we tried to crystallize the complex and succeeded to make it plate-like crystal. Diffraction data from the complex crystal were collected by using synchrotron radiation in which the highest resolution leached to seven angstroms. Further trial of the crystallization using several kinds of detergent lead to obtain new crystals.
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[Journal Article] Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure.2009
Author(s)
Tetsuo Yamashita, Yoshio Moria, Naoyuki Miyazaki, R. Holl, Cheng, Masato Yoshimura, Hideaki Unno, Ryoichi Shima, Kohji Moriishi, Tomitake Tsukihara, Tian Cheng Li, Naokazu Takeda, Tatsuo Miyamura, Yoshiharu Matsuura
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Journal Title
Proc Natl Acad Sci U S A. 106(31)
Pages: 12986-12991
Peer Reviewed
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