2010 Fiscal Year Final Research Report
Analysis of the microRNA regulatory mechanisms based on the development of human microRNA expression vectors
| Project/Area Number |
20770133
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Molecular biology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NAITO Yuki The University of Tokyo, 大学院・理学系研究科, 特任助教 (60451829)
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| Project Period (FY) |
2008 – 2010
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| Keywords | マイクロRNA |
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| Research Abstract |
The human microRNA (miRNA) expression vectors and the miRNA sensors were developed in order to investigate the regulatory mechanisms of miRNAs. We present siDirect 2.0 webserver, which provides functional siRNA design with the reduction of the seed-dependent, miRNA-like off-target effects of an siRNA.
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