• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2009 Fiscal Year Final Research Report

Study of the function of Yip1A in Golgi-to-endoplasmic reticulum retrograde transport by using semi-intact cell assay

Research Project

  • PDF
Project/Area Number 20770151
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Cell biology
Research InstitutionThe University of Tokyo

Principal Investigator

KANO Fumi  The University of Tokyo, 大学院・総合文化研究科, 助教 (10361594)

Project Period (FY) 2008 – 2009
Keywords小胞輸送 / セミインタクト細胞 / ゴルジ体 / 小胞体 / 再構成 / Yip1A / 逆行輸送
Research Abstract

We studied the function of Yip1A in the intracellular vesicular transport by establishing the assay for the transports in permeabilized cell "semi-intact cell" system. We found that Yip1A regulated the retrograde transport from the Golgi apparatus to the endoplasmic reticulum (ER), and the results were published in the Journal of Cell Science. We also identified the Yip1A interacting proteins, which would be the possible regulatory components for the Golgi-to-ER transport.

  • Research Products

    (15 results)

All 2011 2010 2009 Other

All Journal Article (6 results) Presentation (8 results) Remarks (1 results)

  • [Journal Article] Hydrogen peroxide depletes phosphatidylinositol-3-phosphate from endosomes in a p38 MAPK-dependent manner and perturbs endocytosis.2011

    • Author(s)
      Kano F, Arai T, Matsuto M, Hayashi H, Sato M, Murata M.
    • Journal Title

      Biochim Biophys Acta.-Mol. Cell Res. 1813

      Pages: 784-801

  • [Journal Article] An orally applicable Shiga toxin neutralizer functions in the intestine to inhibit the intracellular transport of the toxin.2010

    • Author(s)
      Watanabe-Takahashi M, Sato T, Dohi T, Noguchi N, Kano F, Murata M, Hamabata T, Natori Y, Nishikawa K.
    • Journal Title

      Infect Immun 78

      Pages: 178-183

  • [Journal Article] Golgi-associated GSK3beta regulates the sorting process of post-Golgi membrane trafficking.2010

    • Author(s)
      Adachi A, Knano F, Tsuboi T, Fujita M, Maeda Y, Murata M.
    • Journal Title

      J. Cell Sci. 123

      Pages: 3215-3225

  • [Journal Article] Visual screening and analysis for kinase-regulated membrane trafficking pathways that are involved in extensive beta-amyloid secretion.2009

    • Author(s)
      Adachi A, Kano F, Saido TC, Murata M
    • Journal Title

      Genes to Cells 14

      Pages: 355-369

  • [Journal Article] YiplA regulates the retrograde transport form the Golgi apparatus to the endoplasmic reticulum.2009

    • Author(s)
      Kano. F., Yamauchi, S., Yoshida, Y., Watanabe-Takahashi, M., Nishikawa, K., Nakamura, N., Murata. M
    • Journal Title

      Journal of Cell Science 122

      Pages: 2218-2227

  • [Journal Article] Intracellular Phospholipase A1 iPLA1(gamma) is a Novel Factor Involved in COPI- and Rab6-Independent Retrograde Transport between the ER and the Golgi Complex.

    • Author(s)
      Morikawa, R.K., Aoki, J., Kano, F., Murata, M., Yamamoto, A., Tsujimoto, M., Arai, H.
    • Journal Title

      Journal of Biological Chemistry 284

      Pages: 26620-26630

  • [Presentation] p38-dependent loss of phosphatidylinositol-3-phosphate at endosomes affects the retrograde transport of cholera toxin from cell surface to the Golgi BMB20102010

    • Author(s)
      F.Kano, T.Arai, M.Matsuto, M.Murata.
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-08
  • [Presentation] Molecular mechanisms for the targeting of YiplA to ER-Golgi intermediate compartment BMB20102010

    • Author(s)
      田口由起, 加納ふみ, 村田昌之
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-07
  • [Presentation] セミインタクト細胞リシール法を用いたシグナル伝達経路解析システムの構築2010

    • Author(s)
      加納ふみ、荒井珠貴、松戸真理子、村田昌之
    • Organizer
      細胞を創る研究会3.0
    • Place of Presentation
      先端科学技術研究センター
    • Year and Date
      2010-11-12
  • [Presentation] セミインタクト細胞を用いたRab6Aのゴルジ体へのターゲティングの再構成2010

    • Author(s)
      松戸真理子、加納ふみ、荒井珠貴、村田昌之
    • Organizer
      細胞を創る研究会3.0
    • Place of Presentation
      先端科学技術研究センター
    • Year and Date
      2010-11-12
  • [Presentation] Murata Establishment of semi-intact cell system and application of its resealing technique : a study of membrane dynamics2010

    • Author(s)
      F.Kano, T.Arai, M.Matsuto, M.
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学川内キャンパス
    • Year and Date
      2010-09-21
  • [Presentation] セミインタクト細胞を用いたオルガネラダイナミクスの分子機構解明2010

    • Author(s)
      加納ふみ、村田昌之
    • Organizer
      日本薬学会第130年会(招待講演)
    • Place of Presentation
      岡山大学
    • Year and Date
      2010-03-29
  • [Presentation] Mechanistic Insights into Menbrane Dynamics Using Semi-Intact Cell System2009

    • Author(s)
      加納ふみ
    • Organizer
      第47回日本生物物理学会年会(招待講演)
    • Place of Presentation
      徳島文理大学
    • Year and Date
      2009-10-01
  • [Presentation] 生命現象の可視化解析ツールとしてのセミインタクト細胞系2009

    • Author(s)
      加納ふみ
    • Organizer
      日本化学会第3回関東支部大会(招待講演)
    • Place of Presentation
      早稲田大学
    • Year and Date
      2009-09-01
  • [Remarks] ホームページ等

    • URL

      http://muratalab.c.u-tokyo.ac.jp/

URL: 

Published: 2012-02-13   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi