The research of the oil gland secretions from oribatid mites

2009 Fiscal Year Final Research Report

• Project/Area Number: 20780086
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Bioproduction chemistry/Bioorganic chemistry
• Research Institution: Kyoto Gakuen University
• Principal Investigator: SHIMIZU Nobuhiro Kyoto Gakuen University, バイオ環境学部, 講師 (30434658)
• Project Period (FY): 2008 – 2009
• Keywords: ササラダニ / アルカロイド / テルペン / イリドイド / 防御物質 / 有機合成

Research Abstract

This study analyzed the secretions of the oil glands of oribatid mites collected from the field on our campus of Kyoto Gakuen University in Kameoka, Kyoto Prefecture. Poison-frog alkaloids different from pumiliotoxins identified in 2005 were newly detected by GC/MS analyses. Iridoid monoterpene known to serve as a defensive compound in leaf beetle larvae was first identified from oribatid mites. To determine the absolute stereochemistry, we accomplished an enantioselective synthesis to obtain an optically active compound. Furthermore, the stereochemistry of two female-specific normonoterpenes detected from related astigmatid mite was determined by GC analyses with chiral column.

Research Products

• [Journal Article] Peumusolide A, unprecedented NES non-antagonistic inhibitor for nuclear export of MEK (2010)
  • Author(s): Tamura, S., Hattori, Y., Kaneko, M., Shimizu, N., Tanimura, S., Kohno, M., Murakami, N.
  • Journal Title: Tetrahedron Letters 51 Pages: 1678-1681
  • Peer Reviewed
• [Journal Article] (R)-(-)-Linalyl acetate and (S)-(-)-germacrene D from the leaves of Mexican Bursera linanoe. (2010)
  • Author(s): Noge, K., Shimizu, N., Becerra, X.J.
  • Journal Title: Natural Product Communications Pages: 351-354
  • Peer Reviewed
• [Journal Article] Bioisostere of valtrate, anti-HIV principle by inhibition for nuclear export of Rev. (2010)
  • Author(s): Tamura, S., Shimizu, N., Fujiwara, K., Kaneko, M., Kimura, T., Murakami, N.
  • Journal Title: Bioorganic & Medicinal Chemistry Letters 20 Pages: 2159-2162
  • Peer Reviewed
• [Journal Article] Syntheses of bioactive bisabolane-type Cryptomeria japonica sesquiterpenes. (2009)
  • Author(s): Shimizu, N., Kuwahara, Y.
  • Journal Title: Bioscience, Biotechnology, and Biochemistry 73 Pages: 588-591
  • Peer Reviewed
• [Journal Article] Female sex pheromone of a Japanese population of the allium leafminer, Acrolepiopsis sapporensis (Lepidoptera: Acrolepiidae). (2009)
  • Author(s): Shimizu, N., Kuwahara, Y.
  • Journal Title: Journal of Pesticide Science 34 Pages: 181-183
  • Peer Reviewed
• [Journal Article] Stereochemistry of Female Specific Normonoterpenes, Sex Pheromone Candidates from Acarid Mite, Tyreophagus sp. (2009)
  • Author(s): Shimizu, N., Miwa, K., Noge, K., Yakumaru, R., Mori, N., Kuwahara, Y.
  • Journal Title: (Astigmata: Acaridae). Bioscience, Biotechnology, and Biochemistry 73 Pages: 2332-2334
  • Peer Reviewed
• [Journal Article] Mandelonitrile as the defense secretion, and phenylacetonitrile as its biosynthetic precursor in Nedyopus tambanus tambanus (Paradoxomatidae: Polydesmida) (2008)
  • Author(s): Kuwahara, Y., Shimizu, N., Sakamoto, F., Tanabe, T.
  • Journal Title: Japanese Journal of Environmental Entomology and Zoology 19 Pages: 79-84
  • Peer Reviewed
• [Presentation] ササラダニ類が生産するイリドジアールの合成と絶対立体配置 (2010)
  • Author(s): 清水伸泰, 薬丸亮太, 桑原保正
  • Organizer: 日本農芸化学会2010年度大会
  • Place of Presentation: 東京
  • Year and Date: 20100300
• [Presentation] フジヤスデ属種Anaulaciulus sp. からラウリン酸n-ヘキシルを主成分とするワックスの同定 (2009)
  • Author(s): 桑原保正, 清水伸泰, 薬丸亮太, 田辺力
  • Organizer: 日本環境動物昆虫学会年次大会
  • Place of Presentation: 大阪府箕面市
  • Year and Date: 20091100
• [Presentation] 隠気門亜目タテイレコダニ科ダニの共通成分イリドジアールの同定 (2009)
  • Author(s): 清水伸泰, 桑原保正
  • Organizer: 日本農芸化学会2009年度大会
  • Place of Presentation: 岡市
  • Year and Date: 20090300
• [Presentation] オビヤスデ目ヤスデ類における青酸産生の新機構 (2008)
  • Author(s): 桑原保正, 清水伸泰, 田辺力
  • Organizer: 日本環境動物昆虫学会年次大会
  • Place of Presentation: 京都市
  • Year and Date: 20081100
• [Presentation] 日本スギに含まれるトノサマバッタ摂食阻害物質ビサボラン型セスキテルペンの合成 (2008)
  • Author(s): 清水伸泰, 桑原保正
  • Organizer: 日本農芸化学会関西支部大会
  • Place of Presentation: 京都府亀岡市
  • Year and Date: 20080900