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2009 Fiscal Year Final Research Report

Prevention of rumen acidosis by the modification of quorum sensing in ruminal bacteria

Research Project

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Project/Area Number 20780196
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Zootechnical science/Grassland science
Research InstitutionMeiji University

Principal Investigator

ASANUMA Narito  Meiji University, 農学部, 講師 (50366902)

Project Period (FY) 2008 – 2009
Keywords畜産学 / 栄養学 / 細菌学 / 遺伝子 / 応用微生物
Research Abstract

It is desirable to consider a new strategy to prevent rumen acidosis, which is cased when ruminants are fed high-concentrate diets, because the dose of antibiotics and ionophores may cause the risk of residual antibiotics in animal products. Therefore, to prevent the overgrowth of the bacterium causing rumen acidosis (Streptococcus bovis), I identified a chemical signaling molecule to control the growth, which may be related to the change in the expression of several proteins, in S. bovis. This result may contribute to the development of a new strategy for the control of S. bovis overgrowth and the prevention of rumen acidosis.

  • Research Products

    (28 results)

All 2010 2009 2008 Other

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (23 results) Remarks (1 results)

  • [Journal Article] Molecular and biochemical characterization of phosphoenolpyruvate carboxykinase in the ruminal bacterium Ruminococcus albus.2009

    • Author(s)
      Asanuma, N., K. Yoshizawa, K. Kanada, T. Hino
    • Journal Title

      Current Microbiology 58

      Pages: 416-420

    • Peer Reviewed
  • [Journal Article] Properties and role of pyruvate kinase in a ruminal bacterium, Streptococcus bovis.2009

    • Author(s)
      Asanuma, N., K. Yoshizawa, T. Hino
    • Journal Title

      Current Microbiology 58

      Pages: 283-287

    • Peer Reviewed
  • [Journal Article] Dietary sphingomyelin alleviates experimental inflammatory bowel disease in mice.2008

    • Author(s)
      Furuya, H., S. Ohkawara, K. Nagashima, N. Asanuma, T. Hino
    • Journal Title

      nternational Journal for vitamin and nutrition research 78

      Pages: 41-49

    • Peer Reviewed
  • [Journal Article] Molecular properties and transcriptional control of the phosphofructokinase and pyruvate kinase genes in a ruminal bacterium2008

    • Author(s)
      sanuma, N., K. Kanada, T. Hino
    • Journal Title

      Streptococcus bovis. Anaerobe 14

      Pages: 237-241

    • Peer Reviewed
  • [Presentation] ルーメン細菌Streptococcus bovisにおけるペプチドホルモンComCの特性とその役割2010

    • Author(s)
      金田和大・市川達也・川村顕子・浅沼成人・日野常男
    • Organizer
      日本畜産学会第112回大会
    • Place of Presentation
      明治大学
    • Year and Date
      2010-03-28
  • [Presentation] Molecular properties and significance of phosphoenolpyruvate carboxykinase in a ruminal bacterium2009

    • Author(s)
      Kanada, K., N. Asanuma, T. Hino
    • Organizer
      Streptococcus bovis. BioMicroWorld2009
    • Place of Presentation
      ポルトガルリスボン
    • Year and Date
      2009-12-03
  • [Presentation] in a ruminal bacterium, Streptococcus bovis.2009

    • Author(s)
      Asanuma, N., T. Ichikawa, A. Kawamura, T. Hino. Auto-inducing peptides, comC, D, E
    • Organizer
      BioMicroWorld2009
    • Place of Presentation
      ポルトガルリスボン
    • Year and Date
      2009-12-03
  • [Presentation] ルーメン共生微生物の情報伝達による環境応答2009

    • Author(s)
      浅沼成人
    • Organizer
      極限環境微生物学会第10回大会
    • Place of Presentation
      明治大学
    • Year and Date
      2009-10-28
  • [Presentation] Streptococcus bovisにおけるホスホエノールピルビン酸カルボキシキナーゼの特性とその役割2009

    • Author(s)
      金田和大・浅沼成人・市川達也・川村顕子・日野常男
    • Organizer
      日本畜産学会第111回大会
    • Place of Presentation
      琉球大学
    • Year and Date
      2009-09-29
  • [Presentation] Presence of sensor histidine kinase and its response regulator in the ruminal bacterium Streptococcus bovis.2009

    • Author(s)
      Ichikawa, T., N. Asanuma, T. Hino
    • Organizer
      The 7th Korea Japan China joint symposium on rumen metabolism and physiology
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-08-06
  • [Presentation] Oxaloacetate-producing enzymes in several ruminal bacteria2009

    • Author(s)
      Kanada, K., N. Asanuma, T. Hino
    • Organizer
      with special reference to phosphoenolpyruvate carboxykinase
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-08-06
  • [Presentation] Effect of Selenomonas ruminantium and Wolinella2009

    • Author(s)
      Kawamura, A., N. Asanuma, T. Hino
    • Organizer
      succinogenes addition on the suppression of nitrosation in the cultures of mixed intestinal bacteria from dogs and cats
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-08-06
  • [Presentation] Quorum sensing system in the ruminal bacterium Streptococcus bovis; Possible strategy for controlling overgrowth of Streptococcus bovis in the rumen.2009

    • Author(s)
      Asanuma, N
    • Organizer
      The 7th Korea Japan China joint symposium on rumen metabolism and physiology
    • Place of Presentation
      韓国ソウル
    • Year and Date
      2009-08-05
  • [Presentation] ルーメンバクテリアにおけるコハク酸経路に関する酵素の解析2009

    • Author(s)
      金田和大・浅沼成人・日野常男
    • Organizer
      第8回微生物研究会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-05-30
  • [Presentation] Streptococcus bovisにおける二成分制御系タンパクの分子生物学的解析2009

    • Author(s)
      市川達也・浅沼成人・日野常男
    • Organizer
      第8回微生物研究会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-05-30
  • [Presentation] Butyrivibrio fibrisolvensの経口投与が動物の増体に及ぼす影響2009

    • Author(s)
      内山嵩雄・藤原悠・鈴木健太・古谷英樹・三輪岳宏・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] 脂肪酸取込み能の高いビフィズス菌株の脂肪酸取込み機構の解明2009

    • Author(s)
      末永万里・川又憲二・佐藤薫・安嶋達郎・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] 乳肉中の共役リノール酸の増加を目的としたルーメンからのバクセン酸流出量の増加法2009

    • Author(s)
      川又憲二・執行百子・末永万里・安嶋達朗・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] ルーメン細菌Streptococcus bovisにおける二成分制御系ホモログタンパクの分子生物学的解析2009

    • Author(s)
      金田和大・市川達也・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] ルーメンバクテリアにおけるPEP carboxykinaseの特性とコハク酸経路との関連2009

    • Author(s)
      吉澤仁雄・市川達也・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] Selenomonas ruminantiumの添加による大腸内におけるニトロソアミン生成の抑制2009

    • Author(s)
      新井雄介・市川達也・浅沼成人・日野常男
    • Organizer
      第110回日本畜産学会大会
    • Place of Presentation
      日本大学
    • Year and Date
      2009-03-27
  • [Presentation] Molecular properties and transcription of the phosphoenolpyruvate carboxykinase gene in a ruminal bacterium2009

    • Author(s)
      Asanuma, N., K. Yoshizawa, K. Kanada, T. Hino
    • Organizer
      Ruminococcus albus. 2009 Conference on gastrointestinal function meeting
    • Place of Presentation
      メリカシカゴ
    • Year and Date
      2009-03-21
  • [Presentation] Molecular properties and transcriptional control of the phosphoenolpyruvate carboxykinase gene in a ruminal bacterium, Streptococcus bovis.2008

    • Author(s)
      Kanada, K., N. Asanuma, T. Hino
    • Organizer
      The 13th Animal science congress of the Asian - Australasian association of animal production societies
    • Place of Presentation
      ベトナムハノイ
    • Year and Date
      20080923-20080924
  • [Presentation] Presence of the two-component regulatory system ComDE, and influence of peptide pheromone ComC on the growth of a ruminal bacterium, Streptococcus bovis.2008

    • Author(s)
      Kanada, K., N. Asanuma, T. Hino
    • Organizer
      6th INRA-RRI Symposium Gut Microbiome
    • Place of Presentation
      フランスクレルモン
    • Year and Date
      20080618-20080620
  • [Presentation] 天然グルコシルセラミド分解能を持つ新種菌の単離・同定2008

    • Author(s)
      古谷英樹・井出由香里・浜本牧子・浅沼成人・日野常男
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-11
  • [Presentation] Selenomonas ruminantiumのF1F0-ATP合成酵素(F1F0-ATP synthase)の遺伝子構造とその転写発現の解析2008

    • Author(s)
      金田和大・浅沼成人・日野常男
    • Organizer
      第37回ルーメン研究会
    • Place of Presentation
      三重大学
    • Year and Date
      2008-09-07
  • [Presentation] treptococcus bovisにおけるホスホエノールピルビン酸カルボキシキナーゼの分子生物学的特性と酵素特性2008

    • Author(s)
      吉澤仁雄・浅沼成人・金田和大・新井雄介・日野常男
    • Organizer
      第37回ルーメン研究会
    • Place of Presentation
      三重大学
    • Year and Date
      2008-09-07
  • [Remarks]

    • URL

      http://www.isc.meiji.ac.jp/~asalab/

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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