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2010 Fiscal Year Final Research Report

Characterization of the structures and roles of glycoconjugates in pasture-based milk for manufacturing of high quality cheese

Research Project

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Project/Area Number 20780197
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Zootechnical science/Grassland science
Research InstitutionNational Agricultural Research Organization

Principal Investigator

ASAKUMA Sadaki  National Agricultural Research Organization, 北海道農業研究センター, 任期付研究員 (50374773)

Project Period (FY) 2008 – 2010
Keywords畜産学 / 乳 / 放牧飼養 / 糖鎖 / シアル酸 / 複合糖質 / チーズ / 乳製品
Research Abstract

Almost 50% of milk productions in Japan have been performed in Hokkaido region, where dairy cows are mainly fed in pasture with more than 60% from May to October. However, little is known regarding the quality of this milk with respect of pasture-based feeding. The purpose of the present study was to clarify the influence, especially for sugar compositions in milk by grazing. There was no difference in hexose concentration (neutral sugar fractions) between grazing and non grazing groups during the experimental period, while total sialic acid concentration (acidic sugar fractions) in the milk of each grazing cow significantly increased compared with that at 0 d of the experimental period. These results indicate that grazing management could have increased the concentration of sialylglycoconjugates in milk. It needs to study the reason and effect of this increasing of total sialic acid concentration in milk by grazing management, near future.

  • Research Products

    (5 results)

All 2010 2008

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (3 results)

  • [Journal Article] Effect of grazing on the concentrations of total sialic acid and hexose in bovine milk.2010

    • Author(s)
      Asakuma S, Ueda Y, Akiyama F, Uemura Y, Miyaji M, Nakamura M, Murai M, Urashima T
    • Journal Title

      Journal of Dairy Science 93

      Pages: 4850-1854

    • Peer Reviewed
  • [Journal Article] Effect of human milk oligosaccharides on messenger ribonucleic acid expression of Toll-like receptor 2 and 4, and of MD2 in the intestinal cell line HT-29.2010

    • Author(s)
      Asakuma S, Yokoyama T, Kimura K, Watanabe Y, Nakamura T, Fukuda K, Urashima T
    • Journal Title

      Journal of Applied Glycoscience 57

      Pages: 177-183

    • Peer Reviewed
  • [Presentation] 放牧飼養及び舎飼い飼養による乳中シアル酸濃度への影響2010

    • Author(s)
      朝隈貞樹, 上田靖子, 秋山典昭, 上村祐介, 宮地慎, 中村正斗, 浦島匡
    • Organizer
      平成22年度日本酪農科学会シンポジウム要旨
    • Year and Date
      20100800
  • [Presentation] 放牧飼養が牛乳及びチーズにおけるシアル酸濃度に及ぼす影響2008

    • Author(s)
      朝隈貞樹, 上田靖子, 秋山典昭
    • Organizer
      2008年度日本酪農科学シンポジウム
    • Year and Date
      20080800
  • [Presentation] 各種ミルクオリゴ糖がヒト腸管由来細胞においてToll様受容体遺伝子発現に及ぼす影響2008

    • Author(s)
      朝隈貞樹, 横山朋子, 木村一雅(ヤクルト), 渡辺陽子, 中村正, 荒井威吉, 福田健二, 浦島匡
    • Organizer
      第28回日本糖質学会年会
    • Year and Date
      20080800

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Published: 2012-02-13   Modified: 2016-04-21  

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